RJR 2403 oxalate | Tocris Bioscience 1053 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

RJR 2403 oxalate

catalog :

1053

quantity :

10 mg (also 50 mg)

price :

151 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Kiss T, Krajcs N, Pirger Z, HernÃ¡di L. Nicotinic acetylcholine receptors containing the Î±7-like subunit mediate contractions of muscles responsible for space positioning of the snail, Helix pomatia L. tentacle. PLoS ONE. 2014;9:e109538 pubmed publisher
Zhong C, Talmage D, Role L. Nicotine elicits prolonged calcium signaling along ventral hippocampal axons. PLoS ONE. 2013;8:e82719 pubmed publisher
Scholze P, Ciuraszkiewicz A, Groessl F, Orr Urtreger A, McIntosh J, Huck S. ?4?2 nicotinic acetylcholine receptors in the early postnatal mouse superior cervical ganglion. Dev Neurobiol. 2011;71:390-9 pubmed publisher
Zakharova E, Storozheva Z, Dudchenko A, Kubatiev A. Chronic cerebral ischaemia forms new cholinergic mechanisms of learning and memory. Int J Alzheimers Dis. 2010;2010:954589 pubmed publisher
Li Y, LaCroix C, Freeling J. Specific subtypes of nicotinic cholinergic receptors involved in sympathetic and parasympathetic cardiovascular responses. Neurosci Lett. 2009;462:20-3 pubmed publisher
Liu Q, Huang Y, Xue F, Simard A, Dechon J, Li G, et al. A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. J Neurosci. 2009;29:918-29 pubmed publisher

product information

brand :

Tocris

master code :

1053

SKU :

1053/10

product name :

RJR 2403 oxalate

description :

Selective 4 2 nAChR agonist

target :

Nicotinic (a4b2) Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

252.27

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

A neuronal nicotinic receptor agonist, showing high selectivity for the 4 2 subtype (Ki values are 26 and 36000 nM for 4 2 and 7 receptors respectively). Active in vivo .

catalog number base :

1053

product keywords :

4 2 selective nicotinic agonists a4b2 Nicotinic Receptors Acetylcholine nAChR RJR2403 oxalate Metanicotine TC-2403 Nicotinic (a4b2) Receptors 1053,

extended description :

Selective 4 2 nAChR agonist

chemical name text :

(E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amine oxalate

formula :

C 10 H 14 N 2 .C 2 H 2 O 4

formula text :

C10H14N2.C2H2O4

cas num :

220662-95-3

2020 USD :

145

2021 USD :

151 USD

alt names :

Metanicotine, TC-2403

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage