product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1053/10
catalog :
1053/10
quantity :
10 mg (also 50 mg)
price :
191 USD
more info or order :
citations: 6
Reference
Kiss T, Krajcs N, Pirger Z, Hernádi L. Nicotinic acetylcholine receptors containing the α7-like subunit mediate contractions of muscles responsible for space positioning of the snail, Helix pomatia L. tentacle. PLoS ONE. 2014;9:e109538 pubmed publisher
Zhong C, Talmage D, Role L. Nicotine elicits prolonged calcium signaling along ventral hippocampal axons. PLoS ONE. 2013;8:e82719 pubmed publisher
Scholze P, Ciuraszkiewicz A, Groessl F, Orr Urtreger A, McIntosh J, Huck S. ?4?2 nicotinic acetylcholine receptors in the early postnatal mouse superior cervical ganglion. Dev Neurobiol. 2011;71:390-9 pubmed publisher
Zakharova E, Storozheva Z, Dudchenko A, Kubatiev A. Chronic cerebral ischaemia forms new cholinergic mechanisms of learning and memory. Int J Alzheimers Dis. 2010;2010:954589 pubmed publisher
Li Y, LaCroix C, Freeling J. Specific subtypes of nicotinic cholinergic receptors involved in sympathetic and parasympathetic cardiovascular responses. Neurosci Lett. 2009;462:20-3 pubmed publisher
Liu Q, Huang Y, Xue F, Simard A, Dechon J, Li G, et al. A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. J Neurosci. 2009;29:918-29 pubmed publisher
product information
master code :
1053
SKU :
1053/10
product name :
RJR 2403 oxalate
unit size :
10 mg (also 50 mg)
description :
Selective 4 2 nAChR agonist
target :
Nicotinic (a4b2) Receptor Agonists
category :
Small Molecules
purity :
99%
observed molecular weight :
252.27
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
RJR 2403 oxalate is a neuronal nicotinic receptor agonist, showing high selectivity for the 4 2 subtype (Ki values are 26 and 36000 nM for 4 2 and 7 receptors respectively). Active in vivo .
top caption :
Selective 4 2 nAChR agonist
extended description :
Selective 4 2 nAChR agonist
chemical name text :
(E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amine oxalate
formula :
C10H14N2.C2H2O4
formula text :
C10H14N2.C2H2O4
cas num :
220662-95-3
USD :
191 USD
product details :
Selective 4 2 nAChR agonist
alt names :
Metanicotine,TC-2403
storage :
Desiccate at +4░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK