Zardaverine | Tocris Bioscience 1046/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Zardaverine

catalog :

1046/10

quantity :

10 mg (also 50 mg)

price :

188 USD

citations: 5

Reference
Navarro G, Quiroz C, Moreno Delgado D, Sierakowiak A, McDowell K, Moreno E, et al. Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine. J Neurosci. 2015;35:6639-53 pubmed publisher
Lee G, Subramanian N, Kim A, Aksentijevich I, Goldbach Mansky R, Sacks D, et al. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature. 2012;492:123-7 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Gulyani S, Earley C, Camandola S, Maudsley S, Ferre S, Mughal M, et al. Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells. Exp Neurol. 2009;215:236-42 pubmed publisher
Zerani M, Boiti C, Zampini D, Brecchia G, Dall Aglio C, Ceccarelli P, et al. Ob receptor in rabbit ovary and leptin in vitro regulation of corpora lutea. J Endocrinol. 2004;183:279-88 pubmed

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1046

SKU :

1046/10

product name :

Zardaverine

description :

PDE3/4 inhibitor

target :

Phosphodiesterase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

268.22

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Zardaverine is a phosphodiesterase inhibitor, selective for PDE3 and 4 (IC50 values are 0.5 and 0.8 M respectively).

product keywords :

PDE3/4 inhibitors inhibits Phosphodiesterases Phosphodiesterases 1046,

extended description :

PDE3/4 inhibitor

chemical name text :

6-[4-(Difluoromethoxy)-3-methoxyphenyl]-3(2H)-pyridazinone

formula :

C12H10F2N2O3

formula text :

C12H10F2N2O3

cas num :

101975-10-4

USD :

186

USD 2025 :

188 USD

product details :

PDE3/4 inhibitor