product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Fluvoxamine maleate
catalog :
1033
quantity :
10 mg (also 50 mg)
price :
78 USD
more info or order :
citations: 8
Reference
Nolan T, Geffert L, Kolber B, Madura J, Surratt C. Discovery of novel-scaffold monoamine transporter ligands via in silico screening with the S1 pocket of the serotonin transporter. ACS Chem Neurosci. 2014;5:784-92 pubmed publisher
Su D, Jiang R, Liu N, Ding L, Wang D, Yu H, et al. Effects of BD1047, a ?1 receptor antagonist, on the expression of mTOR, Camk2? and GSK-3? in fluvoxamine-treated N2a cells. Exp Ther Med. 2014;7:435-438 pubmed
Agarwal J, Zhu Y, Zhang Q, Mongin A, Hough L. TRAM-34, a putatively selective blocker of intermediate-conductance, calcium-activated potassium channels, inhibits cytochrome P450 activity. PLoS ONE. 2013;8:e63028 pubmed publisher
Fishback J, Rosen A, Bhat R, McCurdy C, Matsumoto R. A 96-well filtration method for radioligand binding analysis of ? receptor ligands. J Pharm Biomed Anal. 2012;71:157-61 pubmed publisher
Wood W, Lovell P, Mello C, Perkel D. Serotonin, via HTR2 receptors, excites neurons in a cortical-like premotor nucleus necessary for song learning and production. J Neurosci. 2011;31:13808-15 pubmed publisher
O Donnell E, Saili K, Koch D, Kopparapu P, Farrer D, Bisson W, et al. The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor. PLoS ONE. 2010;5: pubmed publisher
Hirano K, Kimura R, Sugimoto Y, Yamada J, Uchida S, Kato Y, et al. Relationship between brain serotonin transporter binding, plasma concentration and behavioural effect of selective serotonin reuptake inhibitors. Br J Pharmacol. 2005;144:695-702 pubmed
Kobayashi T, Washiyama K, Ikeda K. Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs. Neuropsychopharmacology. 2004;29:1841-51 pubmed
product information
brand :
Tocris
master code :
1033
SKU :
1033/10
product name :
Fluvoxamine maleate
description :
5-HT reuptake inhibitor
target :
5-HT Transporter Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
434.41
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective serotonin reuptake inhibitor; antidepressant. Binds to the human 5-HT transporter with a Ki of 1.6 nmol/l.
catalog number base :
1033
product keywords :
High affinity 1 sigma1 ligands 5-HT reuptake inhibitors inhibits Receptors Serotonin Transporters SERT 5-Hydroxytryptamine Monoamine Neurotransmitter 5-HT Transporters Sigma1 Receptors 1033,
extended description :
5-HT reuptake inhibitor
chemical name text :
(E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate
formula :
C 15 H 21 F 3 N 2 O 2 .C 4 H 4 O 4
formula text :
C15H21F3N2O2.C4H4O4
cas num :
61718-82-9
2020 USD :
75
2021 USD :
78 USD
storage :
Desiccate at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK