CP 93129 dihydrochloride | Tocris Bioscience 1032 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CP 93129 dihydrochloride

catalog :

1032

quantity :

10 mg (also 50 mg)

price :

182 USD

more info or order :

Tocris Bioscience product webpage

citations: 9

Reference
Zhou M, Sun F, Xu C, Chen H, Qiao H, Cai X, et al. Modulation of Kalirin-7 expression by hippocampal CA1 5-HT1B receptors in spatial memory consolidation. Behav Brain Res. 2019;356:148-155 pubmed publisher
Medrihan L, Sagi Y, Inde Z, Krupa O, Daniels C, Peyrache A, et al. Initiation of Behavioral Response to Antidepressants by Cholecystokinin Neurons of the Dentate Gyrus. Neuron. 2017;95:564-576.e4 pubmed publisher
Hirono M, Nagao S, Yanagawa Y, Konishi S. Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells. Neuropharmacology. 2017;118:79-89 pubmed publisher
Majeed Z, Abdeljaber E, Soveland R, Cornwell K, Bankemper A, Koch F, et al. Modulatory Action by the Serotonergic System: Behavior and Neurophysiology in Drosophila melanogaster. Neural Plast. 2016;2016:7291438 pubmed publisher
Watts S, Darios E, Seitz B, Thompson J. 5-HT is a potent relaxant in rat superior mesenteric veins. Pharmacol Res Perspect. 2015;3:e00103 pubmed publisher
Guo J, Rainnie D. Presynaptic 5-HT(1B) receptor-mediated serotonergic inhibition of glutamate transmission in the bed nucleus of the stria terminalis. Neuroscience. 2010;165:1390-401 pubmed publisher
Watakabe A, Komatsu Y, Sadakane O, Shimegi S, Takahata T, Higo N, et al. Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses. Cereb Cortex. 2009;19:1915-28 pubmed publisher
Heisler L, Jobst E, Sutton G, Zhou L, Borok E, Thornton Jones Z, et al. Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron. 2006;51:239-49 pubmed
Rau K, Birdsall E, Volz T, Riordan J, Baucum A, Adair B, et al. Methamphetamine administration reduces hippocampal vesicular monoamine transporter-2 uptake. J Pharmacol Exp Ther. 2006;318:676-82 pubmed

product information

brand :

Tocris

master code :

1032

SKU :

1032/10

product name :

CP 93129 dihydrochloride

description :

5-HT1B agonist

target :

5-HT1B Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

observed molecular weight :

288.18

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and highly selective 5-HT1B agonist (Ki values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT1B, 5-HT1D, 5-HT1A, 5-HT1c and 5-HT2, respectively). Reduces food intake and decreases body weight in rats.

catalog number base :

1032

product keywords :

5-HT1B agonist Serotonin Receptors CP93129 dihydrochloride Pfizer 5-HT1B Receptors 1032,

extended description :

5-HT1B agonist

chemical name text :

1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride

formula :

C 12 H 13 N 3 O.2HCl

formula text :

C12H13N3O.2HCl

cas num :

879089-64-2

2020 USD :

176

2021 USD :

182 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage