product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
1030/10
catalog :
1030/10
quantity :
10 mg (also 50 mg)
price :
111 USD
more info or order :
citations: 5
Reference
Harris N, Isaac A, Gunther A, Merkel K, MELCHIOR J, Xu M, et al. Dorsal BNST α2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors. J Neurosci. 2018;38:8922-8942 pubmed publisher
An K, Jung J, Jeong A, Kim H, Jung S, Lee K, et al. Neuritin can normalize neural deficits of Alzheimer's disease. Cell Death Dis. 2014;5:e1523 pubmed publisher
Hamby M, Coppola G, Ao Y, Geschwind D, Khakh B, Sofroniew M. Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. J Neurosci. 2012;32:14489-510 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Shields A, Wang Q, Winder D. alpha2A-adrenergic receptors heterosynaptically regulate glutamatergic transmission in the bed nucleus of the stria terminalis. Neuroscience. 2009;163:339-51 pubmed publisher
product information
master code :
1030
SKU :
1030/10
product name :
Guanfacine hydrochloride
unit size :
10 mg (also 50 mg)
description :
2A agonist
target :
Adrenergic alpha-2 Receptor Agonists
category :
Small Molecules
purity :
99%
observed molecular weight :
282.56
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Guanfacine hydrochloride is a selective 2A-adrenoceptor agonist (Kd = 31 nM). Displays 60-fold selectivity over 2B-adrenoceptors.
top caption :
2A agonist
extended description :
2A agonist
chemical name text :
[(2,6-Dichlorophenyl)acetyl]guanidine hydrochloride
formula :
C9H9Cl2N3O.HCl
formula text :
C9H9Cl2N3O.HCl
cas num :
29110-48-3
USD :
111 USD
product details :
2A agonist
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK