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company name :
Tocris Bioscience
product type :
chemical
product name :
Nisoxetine hydrochloride
catalog :
1025
quantity :
10 mg (also 50 mg)
price :
125 USD
more info or order :
citations: 5
Reference
Stampanoni Bassi M, Gentile A, Iezzi E, Zagaglia S, Musella A, Simonelli I, et al. Transient Receptor Potential Vanilloid 1 Modulates Central Inflammation in Multiple Sclerosis. Front Neurol. 2019;10:30 pubmed publisher
Poulin H, Bruhova I, Timour Q, Thériault O, Beaulieu J, Frassati D, et al. Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics. Mol Pharmacol. 2014;86:378-89 pubmed publisher
Nolan T, Geffert L, Kolber B, Madura J, Surratt C. Discovery of novel-scaffold monoamine transporter ligands via in silico screening with the S1 pocket of the serotonin transporter. ACS Chem Neurosci. 2014;5:784-92 pubmed publisher
Xu T, Ma Q, Spealman R, Yao W. Amphetamine modulation of long-term potentiation in the prefrontal cortex: dose dependency, monoaminergic contributions, and paradoxical rescue in hyperdopaminergic mutant. J Neurochem. 2010;115:1643-54 pubmed publisher
Li Y, Xi D, Roman J, Huang Y, Gao W. Activation of glycogen synthase kinase-3 beta is required for hyperdopamine and D2 receptor-mediated inhibition of synaptic NMDA receptor function in the rat prefrontal cortex. J Neurosci. 2009;29:15551-63 pubmed publisher
product information
brand :
Tocris
master code :
1025
SKU :
1025/10
product name :
Nisoxetine hydrochloride
description :
Noradrenalin re-uptake inhibitor
target :
Adrenergic Transporter Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
307.82
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
A potent and selective inhibitor of noradrenalin uptake with little or no affinity for a range of other neurotransmitter receptors.
catalog number base :
1025
product keywords :
Noradrenalin reuptake inhibitors inhibits Transporters NET Adrenergic Monoamine Neurotransmitter noradrenaline Adrenergic Transporters 1025,
extended description :
Noradrenalin re-uptake inhibitor
chemical name text :
( )- -(2-Methoxyphenoxy)-N-methylbenzenepropanamine hydrochloride
formula :
C 17 H 21 NO 2 .HCl
formula text :
C17H21NO2.HCl
cas num :
57754-86-6
2020 USD :
122
2021 USD :
125 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK