product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CGP 20712 dihydrochloride
catalog :
1024
quantity :
10 mg (also 50 mg)
price :
227 USD
more info or order :
citations: 16
Reference |
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Crestani C, Alves F, Resstel L, Correa F. Both alpha1 and alpha2-adrenoceptors mediate the cardiovascular responses to noradrenaline microinjected into the bed nucleus of the stria terminal of rats. Br J Pharmacol. 2008;153:583-90 pubmed
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Jane wit D, Altuntas C, Johnson J, Yong S, Wickley P, Clark P, et al. Beta 1-adrenergic receptor autoantibodies mediate dilated cardiomyopathy by agonistically inducing cardiomyocyte apoptosis. Circulation. 2007;116:399-410 pubmed
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product information
brand :
Tocris
master code :
1024
SKU :
1024/10
product name :
CGP 20712 dihydrochloride
description :
Highly potent and selective 1 antagonist
target :
Adrenergic beta-1 Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
96%
observed molecular weight :
567.39
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Highly selective and potent 1-adrenoceptor antagonist (IC50 = 0.7 nM). Displays 10,000-fold selectivity over 2-adrenoceptors. Also available as part of the -Adrenoceptor Antagonist Tocriset .
catalog number base :
1024
product keywords :
potent selective 1-adrenoceptor beta1-adrenoceptor b1-adrenoceptor 1-Adrenergic beta1-Adrenergic b1-adrenergic antagonist Receptors CGP20712 dihydrochloride CGP 20712A CGP20712A Adrenergic Beta-1 Receptors 1024,
extended description :
Highly potent and selective 1 antagonist
chemical name text :
1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride
formula :
C 23 H 25 F 3 N 4 O 5 .2HCl
formula text :
C23H25F3N4O5.2HCl
cas num :
1216905-73-5
2020 USD :
218
2021 USD :
227 USD
storage :
Desiccate at +4°C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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