LY 225910 | Tocris Bioscience 1018/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LY 225910

catalog :

1018/10

quantity :

10 mg (also 50 mg)

price :

146 USD

citations: 4

Reference
Seillier A, Martinez A, Giuffrida A. Phencyclidine-induced social withdrawal results from deficient stimulation of cannabinoid CB? receptors: implications for schizophrenia. Neuropsychopharmacology. 2013;38:1816-24 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Karson M, Whittington K, Alger B. Cholecystokinin inhibits endocannabinoid-sensitive hippocampal IPSPs and stimulates others. Neuropharmacology. 2008;54:117-28 pubmed
Gallopin T, Geoffroy H, Rossier J, Lambolez B. Cortical sources of CRF, NKB, and CCK and their effects on pyramidal cells in the neocortex. Cereb Cortex. 2006;16:1440-52 pubmed

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1018

SKU :

1018/10

product name :

LY 225910

description :

Potent CCK2 antagonist

target :

CCK2 Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

storage :

Desiccate at -20°C

observed molecular weight :

502.41

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

LY 225910 is a potent CCK2 receptor antagonist (IC50 = 9.3 nM for inhibition of 125I-labeled CCK-8 sulfate binding at mouse brain membranes).

product keywords :

Potent CCK2 antagonists Cholecystokinin2 Receptors LY225910 CCK2 Receptor 1018,

extended description :

Potent CCK2 antagonist

chemical name text :

2-[2-(5-Bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]-4-(3H)-quinazoline

formula :

C27H24BrN3O2

formula text :

C27H24BrN3O2

cas num :

133040-77-4

USD :

144

USD 2025 :

146 USD

product details :

Potent CCK2 antagonist