L-741,742 hydrochloride | Tocris Bioscience 1004 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L-741,742 hydrochloride

catalog :

1004

quantity :

10 mg (also 50 mg)

price :

159 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Dolma S, Selvadurai H, Lan X, Lee L, Kushida M, Voisin V, et al. Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell. 2016;29:859-873 pubmed publisher
Root D, Hoffman A, Good C, Zhang S, Gigante E, Lupica C, et al. Norepinephrine activates dopamine D4 receptors in the rat lateral habenula. J Neurosci. 2015;35:3460-9 pubmed publisher
Bastianetto S, Danik M, Mennicken F, Williams S, Quirion R. Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation. BMC Neurosci. 2006;7:28 pubmed

product information

brand :

Tocris

master code :

1004

SKU :

1004/10

product name :

L-741,742 hydrochloride

description :

Highly selective D4 antagonist

target :

Dopamine D4 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

417.38

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

A potent and highly selective D4 dopamine receptor antagonist, with Ki values of 1700, 770 and 3.5 nM at cloned human D2, D3 and D4 receptors.

catalog number base :

1004

product keywords :

selective D4 antagonists Dopamine Receptors dopaminergic L741742 D4 Receptors 1004,

extended description :

Highly selective D4 antagonist

chemical name text :

5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole hydrochloride

formula :

C 23 H 25 N 2 ClO.HCl

formula text :

C23H25N2ClO.HCl

cas num :

874882-93-6

2020 USD :

154

2021 USD :

159 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage