Chlorisondamine diiodide | Tocris Bioscience 1001 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Chlorisondamine diiodide

catalog :

1001

quantity :

10 mg (also 50 mg)

price :

157 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Sabharwal R, Weiss R, Zimmerman K, Domenig O, Cicha M, Chapleau M. Angiotensin-dependent autonomic dysregulation precedes dilated cardiomyopathy in a mouse model of muscular dystrophy. Exp Physiol. 2015;100:776-95 pubmed publisher
Sabharwal R, Cicha M, Sinisterra R, de Sousa F, Santos R, Chapleau M. Chronic oral administration of Ang-(1-7) improves skeletal muscle, autonomic and locomotor phenotypes in muscular dystrophy. Clin Sci (Lond). 2014;127:101-9 pubmed publisher
Bucci M, Vellecco V, Harrington L, Brancaleone V, Roviezzo F, Mattace Raso G, et al. Cross-talk between toll-like receptor 4 (TLR4) and proteinase-activated receptor 2 (PAR(2) ) is involved in vascular function. Br J Pharmacol. 2013;168:411-20 pubmed publisher
Luyer M, Greve J, Hadfoune M, Jacobs J, Dejong C, Buurman W. Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve. J Exp Med. 2005;202:1023-9 pubmed

product information

brand :

Tocris

master code :

1001

SKU :

1001/10

product name :

Chlorisondamine diiodide

description :

nAChR antagonist; slow offset

target :

Additional Nicotinic Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

611.95

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

An exceptionally long lasting nicotinic antagonist (IC50 ~ 1.6 mM); blockade of central nicotinic responses induced by chlorisondamine can persist for several weeks.

catalog number base :

1001

product keywords :

Nicotinic antagonists slow offset Acetylcholine Receptors Non-Selective nAChR 3-[[4-(Chlorophenyl)piperazin-1-yl]methyl-1H-pyrrolo[2,3-b]pyridine diiodide Nicotinic Receptors (Non-selective) 1001,

extended description :

nAChR antagonist; slow offset

chemical name text :

4,5,6,7-Tetrachloro-1,3-dihydro-2-methyl-2-[2-trimethylammonium)ethyl]-2H-isoindolium diiodide

formula :

C 14 H 20 Cl 4 I 2 N 2

formula text :

C14H20Cl4I2N2

cas num :

96750-66-2

2020 USD :

152

2021 USD :

157 USD

alt names :

3-[[4-(Chlorophenyl)piperazin-1-yl]methyl-1 H -pyrrolo[2,3- b ]pyridine diiodide

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage