This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
Chlorisondamine diiodide
catalog :
1001/10
quantity :
10 mg (also 50 mg)
price :
182 USD
citations: 4
Reference
Sabharwal R, Weiss R, Zimmerman K, Domenig O, Cicha M, Chapleau M. Angiotensin-dependent autonomic dysregulation precedes dilated cardiomyopathy in a mouse model of muscular dystrophy. Exp Physiol. 2015;100:776-95 pubmed publisher
Sabharwal R, Cicha M, Sinisterra R, de Sousa F, Santos R, Chapleau M. Chronic oral administration of Ang-(1-7) improves skeletal muscle, autonomic and locomotor phenotypes in muscular dystrophy. Clin Sci (Lond). 2014;127:101-9 pubmed publisher
Bucci M, Vellecco V, Harrington L, Brancaleone V, Roviezzo F, Mattace Raso G, et al. Cross-talk between toll-like receptor 4 (TLR4) and proteinase-activated receptor 2 (PAR(2) ) is involved in vascular function. Br J Pharmacol. 2013;168:411-20 pubmed publisher
Luyer M, Greve J, Hadfoune M, Jacobs J, Dejong C, Buurman W. Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve. J Exp Med. 2005;202:1023-9 pubmed
product information
brand :
Tocris
master code :
1001
SKU :
1001/10
product name :
Chlorisondamine diiodide
description :
nAChR antagonist; slow offset
target :
Additional Nicotinic Receptor Antagonists
category :
Small Molecules
sizes available :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
611.95
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
An exceptionally long lasting nicotinic antagonist (IC50 ~ 1.6 mM); blockade of central nicotinic responses induced by chlorisondamine can persist for several weeks.
extended description :
nAChR antagonist; slow offset
chemical name text :
4,5,6,7-Tetrachloro-1,3-dihydro-2-methyl-2-[2-trimethylammonium)ethyl]-2H-isoindolium diiodide
formula :
C 14 H 20 Cl 4 I 2 N 2
formula text :
C14H20Cl4I2N2
cas num :
96750-66-2
USD :
173
USD 2023 :
182 USD
product details :
nAChR antagonist; slow offset
alt names :
3-[[4-(Chlorophenyl)piperazin-1-yl]methyl-1 H -pyrrolo[2,3- b ]pyridine diiodide
storage :
Desiccate at +4°C
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK