product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0999/100
catalog :
0999/100
quantity :
100 mg
price :
96 USD
more info or order :
citations: 13
Reference
Das B, Dobrowolski C, Luttge B, Valadkhan S, Chomont N, Johnston R, et al. Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir. Proc Natl Acad Sci U S A. 2018;115:E7795-E7804 pubmed publisher
Ronghe A, Chatterjee A, Bhat N, Padhye S, Bhat H. Tamoxifen synergizes with 4-(E)-{(4-hydroxyphenylimino)-methylbenzene, 1,2-diol} and 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, novel azaresveratrol analogs, in inhibiting the proliferation of breast cancer cells. Oncotarget. 2016;7:51747-51762 pubmed publisher
Sheng Y, Sun B, Xie X, Li N, Dong D. DMH1 (4-[6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline) inhibits chemotherapeutic drug-induced autophagy. Acta Pharm Sin B. 2015;5:330-6 pubmed publisher
Todd H, Galea G, Meakin L, Delisser P, Lanyon L, Windahl S, et al. Wnt16 Is Associated with Age-Related Bone Loss and Estrogen Withdrawal in Murine Bone. PLoS ONE. 2015;10:e0140260 pubmed publisher
Bertrand S, Hu C, Aksenova M, Mactutus C, Booze R. HIV-1 Tat and cocaine mediated synaptopathy in cortical and midbrain neurons is prevented by the isoflavone Equol. Front Microbiol. 2015;6:894 pubmed publisher
Gutierrez E, Richardson D, Jansson P. The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. J Biol Chem. 2014;289:33568-89 pubmed publisher
Nicholson T, Moses M, Uchtmann K, Keil K, Bjorling D, Vezina C, et al. Estrogen receptor-α is a key mediator and therapeutic target for bladder complications of benign prostatic hyperplasia. J Urol. 2015;193:722-9 pubmed publisher
Mansouri Attia N, James R, Ligon A, Li X, Pangas S. Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line. Biol Reprod. 2014;91:100 pubmed publisher
Gibbs R, Nelson D, Hammond R. Role of GPR30 in mediating estradiol effects on acetylcholine release in the hippocampus. Horm Behav. 2014;66:339-45 pubmed publisher
Antoon J, Bratton M, Guillot L, Wadsworth S, Salvo V, Burow M. Inhibition of p38-MAPK alters SRC coactivation and estrogen receptor phosphorylation. Cancer Biol Ther. 2012;13:1026-33 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Tremere L, Jeong J, Pinaud R. Estradiol shapes auditory processing in the adult brain by regulating inhibitory transmission and plasticity-associated gene expression. J Neurosci. 2009;29:5949-63 pubmed publisher
Wieland H, Hechtel N, Faigle M, Neumeister B. Efficient intracellular multiplication of Legionella pneumophila in human monocytes requires functional host cell L-type calcium channels. FEMS Immunol Med Microbiol. 2006;47:296-301 pubmed
product information
master code :
999
SKU :
0999/100
product name :
Tamoxifen citrate
unit size :
100 mg
description :
Estrogen receptor partial agonist/antagonist
target :
Estrogen and Related Receptor Modulators
category :
Small Molecules
purity :
99%
observed molecular weight :
563.65
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Tamoxifen citrate is an estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPER. Tamoxifen (Cat. No. 6432) is also available.
top caption :
Estrogen receptor partial agonist/antagonist
extended description :
Estrogen receptor partial agonist/antagonist
chemical name text :
(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine citrate
formula :
C26H29NO.C6H8O7
formula text :
C26H29NO.C6H8O7
cas num :
54965-24-1
USD :
96 USD
product details :
Estrogen receptor partial agonist/antagonist
storage :
Desiccate at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK