0985/10 | Tocris Bioscience 0985/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0985/10

catalog :

0985/10

quantity :

10 mg (also 50 mg)

price :

157 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher

product information

master code :

985

SKU :

0985/10

product name :

RS 17053 hydrochloride

unit size :

10 mg (also 50 mg)

description :

1A antagonist

target :

Adrenergic alpha-1 Receptor Antagonists

category :

Small Molecules

observed molecular weight :

449.42

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

RS 17053 hydrochloride is an 1A-adrenoceptor antagonist, with very high affinity for 1A receptors (pKi and pA2 estimates of 9.1 - 9.9) and a 30 - 100 fold selectivity over the 1B and 1D subtypes (pKi and pA2 estimates 7.7 - 7.8).

top caption :

1A antagonist

extended description :

1A antagonist

chemical name text :

(N-[2-(2-Cyclopropylmethoxyphenoxy)ethyl]-5-chloro- , -dimethyl-1H-indole-3-ethanamine) hydrochloride

formula :

C24H29N2O2Cl.HCl

formula text :

C24H29N2O2Cl.HCl

cas num :

169505-93-5

USD :

157 USD

product details :

1A antagonist

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage