product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0964/100
catalog :
0964/100
quantity :
100 mg
price :
94 USD
more info or order :
citations: 5
Reference
Cox M, Wendler C, Erdelyi I, Beck A, Zeiss C, Rivkees S. CHRONIC NEONATAL DIAZOXIDE THERAPY IS NOT ASSOCIATED WITH ADVERSE EFFECTS. Online J Biol Sci. 2014;14:49-56 pubmed
Sun H, Wei Y, Deng H, Xiong Q, Li M, Lahiri J, et al. Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel. Sci Rep. 2014;4:4934 pubmed publisher
Frazao R, Cravo R, Donato J, Ratra D, Clegg D, Elmquist J, et al. Shift in Kiss1 cell activity requires estrogen receptor ?. J Neurosci. 2013;33:2807-20 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Niu K, Saloman J, Zhang Y, Ro J. Sex differences in the contribution of ATP-sensitive K+ channels in trigeminal ganglia under an acute muscle pain condition. Neuroscience. 2011;180:344-52 pubmed publisher
product information
master code :
964
SKU :
0964/100
product name :
Diazoxide
unit size :
100 mg
description :
Inhibits AMPA desensitization
target :
AMPA Receptor Compounds
category :
Small Molecules
purity :
98%
observed molecular weight :
230.67
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Diazoxide is an antihypertensive, activates ATP-dependent K+ channels (Kir6). Induces activation of PKC , an intermediate in the opening of mitoKATP channels, results in cardioprotection against hypoxia-induced death. Blocks desensitization of AMPA receptors.
top caption :
Inhibits AMPA desensitization
extended description :
Inhibits AMPA desensitization
chemical name text :
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
formula :
C8H7ClN2O2S
formula text :
C8H7ClN2O2S
cas num :
364-98-7
USD :
94 USD
product details :
Inhibits AMPA desensitization
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK