product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Spermine tetrahydrochloride
catalog :
0958
quantity :
100 mg
price :
84 USD
more info or order :
citations: 8
Reference
Kim W, Cho J. Encoding of Discriminative Fear Memory by Input-Specific LTP in the Amygdala. Neuron. 2017;95:1129-1146.e5 pubmed publisher
McGee T, Bats C, Farrant M, Cull Candy S. Auxiliary Subunit GSG1L Acts to Suppress Calcium-Permeable AMPA Receptor Function. J Neurosci. 2015;35:16171-9 pubmed publisher
Quintana P, Soto D, Poirot O, Zonouzi M, Kellenberger S, Muller D, et al. Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons. J Physiol. 2015;593:4373-86 pubmed publisher
Soto D, Coombs I, Gratacòs Batlle E, Farrant M, Cull Candy S. Molecular mechanisms contributing to TARP regulation of channel conductance and polyamine block of calcium-permeable AMPA receptors. J Neurosci. 2014;34:11673-83 pubmed publisher
Zonouzi M, Renzi M, Farrant M, Cull Candy S. Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells. Nat Neurosci. 2011;14:1430-8 pubmed publisher
De Biase L, Kang S, Baxi E, Fukaya M, Pucak M, Mishina M, et al. NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination. J Neurosci. 2011;31:12650-62 pubmed publisher
Campioni M, Xu M, McGehee D. Stress-induced changes in nucleus accumbens glutamate synaptic plasticity. J Neurophysiol. 2009;101:3192-8 pubmed publisher
Soto D, Coombs I, Renzi M, Zonouzi M, Farrant M, Cull Candy S. Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5. Nat Neurosci. 2009;12:277-85 pubmed publisher
product information
brand :
Tocris
master code :
0958
SKU :
0958/100
product name :
Spermine tetrahydrochloride
description :
Modulator at polyamine site
target :
Additional NMDA Receptor Compounds
category :
Small Molecules
unit size :
100 mg
observed molecular weight :
348.19
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Polyamine which produces a variety of modulatory effects on the NMDA receptor channel, acting through a specific site on the complex which can cause both agonist and antagonist effects.
catalog number base :
958
product keywords :
modulators polyamine site Glutamate NMDA Receptors N-Methyl-D-Aspartate iGlur Ionotropic NMDA Receptors 0958,
extended description :
Modulator at polyamine site
chemical name text :
N,N -Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
formula :
C 10 H 26 N 4 .4HCl
formula text :
C10H26N4.4HCl
cas num :
306-67-2
2020 USD :
82
2021 USD :
84 USD
storage :
Desiccate at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK