Brailoiu E, Chakraborty S, Brailoiu G, Zhao P, Barr J, Ilies M, et al. Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP3-Evoked Ca2+ Signals through Sigma-1 Receptors. Cell Rep. 2019;26:330-337.e4 pubmed publisher

Sánchez Blázquez P, Cortés Montero E, Rodríguez Muñoz M, Garzón J. Sigma 1 Receptor Antagonists Inhibit Manic-Like Behaviors in Two Congenital Strains of Mice. Int J Neuropsychopharmacol. 2018;21:938-948 pubmed publisher

Sánchez Blázquez P, Pozo Rodrigálvarez A, Merlos M, Garzón J. The Sigma-1 Receptor Antagonist, S1RA, Reduces Stroke Damage, Ameliorates Post-Stroke Neurological Deficits and Suppresses the Overexpression of MMP-9. Mol Neurobiol. 2018;55:4940-4951 pubmed publisher

Rodríguez Muñoz M, Cortés Montero E, Pozo Rodrigálvarez A, Sánchez Blázquez P, Garzón Niño J. The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders. Oncotarget. 2015;6:35458-77 pubmed publisher

Moon J, Roh D, Yoon S, Choi S, Kwon S, Choi H, et al. σ1 receptors activate astrocytes via p38 MAPK phosphorylation leading to the development of mechanical allodynia in a mouse model of neuropathic pain. Br J Pharmacol. 2014;171:5881-97 pubmed publisher

Pabba M, Wong A, Ahlskog N, Hristova E, Biscaro D, Nassrallah W, et al. NMDA receptors are upregulated and trafficked to the plasma membrane after sigma-1 receptor activation in the rat hippocampus. J Neurosci. 2014;34:11325-38 pubmed publisher

Lesch A, Rubil S, Thiel G. Activation and inhibition of transient receptor potential TRPM3-induced gene transcription. Br J Pharmacol. 2014;171:2645-58 pubmed

Pan B, Guo Y, Kwok W, Hogan Q, Wu H. Sigma-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons. J Pharmacol Exp Ther. 2014;350:290-300 pubmed publisher

Nguyen L, Robson M, Healy J, Scandinaro A, Matsumoto R. Involvement of sigma-1 receptors in the antidepressant-like effects of dextromethorphan. PLoS ONE. 2014;9:e89985 pubmed publisher

Sánchez Blázquez P, Rodríguez Muñoz M, Herrero Labrador R, Burgueno J, Zamanillo D, Garzón J. The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases. Int J Neuropsychopharmacol. 2014;17:1943-55 pubmed publisher

Su D, Jiang R, Liu N, Ding L, Wang D, Yu H, et al. Effects of BD1047, a ?1 receptor antagonist, on the expression of mTOR, Camk2? and GSK-3? in fluvoxamine-treated N2a cells. Exp Ther Med. 2014;7:435-438 pubmed

Gear R, Bogen O, Ferrari L, Green P, Levine J. NOP receptor mediates anti-analgesia induced by agonist-antagonist opioids. Neuroscience. 2014;257:139-48 pubmed publisher

Behensky A, Yasny I, Shuster A, Seredenin S, Petrov A, Cuevas J. Afobazole activation of ?-1 receptors modulates neuronal responses to amyloid-?25-35. J Pharmacol Exp Ther. 2013;347:468-77 pubmed publisher

Kourrich S, Hayashi T, Chuang J, Tsai S, SU T, Bonci A. Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine. Cell. 2013;152:236-47 pubmed publisher

Amer M, McKeown L, Tumova S, Liu R, Seymour V, Wilson L, et al. Inhibition of endothelial cell Ca²? entry and transient receptor potential channels by Sigma-1 receptor ligands. Br J Pharmacol. 2013;168:1445-55 pubmed publisher

Hiranita T, Soto P, Kohut S, Kopajtic T, Cao J, Newman A, et al. Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and ? receptors. J Pharmacol Exp Ther. 2011;339:662-77 pubmed publisher

Roh D, Choi S, Yoon S, Kang S, Moon J, Kwon S, et al. Spinal neuronal NOS activation mediates sigma-1 receptor-induced mechanical and thermal hypersensitivity in mice: involvement of PKC-dependent GluN1 phosphorylation. Br J Pharmacol. 2011;163:1707-20 pubmed publisher

Son J, Kwon Y. Sigma-1 Receptor Antagonist BD1047 Reduces Allodynia and Spinal ERK Phosphorylation Following Chronic Compression of Dorsal Root Ganglion in Rats. Korean J Physiol Pharmacol. 2010;14:359-64 pubmed publisher

Kwon Y, Jeong Y, Kwon J, Son J, Kim K. The Antinociceptive Effect of Sigma-1 Receptor Antagonist, BD1047, in a Capsaicin Induced Headache Model in Rats. Korean J Physiol Pharmacol. 2009;13:425-9 pubmed publisher

Yoon S, Roh D, Seo H, Kang S, Han H, Beitz A, et al. Intrathecal injection of the neurosteroid, DHEAS, produces mechanical allodynia in mice: involvement of spinal sigma-1 and GABA receptors. Br J Pharmacol. 2009;157:666-73 pubmed publisher

Cantarella G, Bucolo C, Di Benedetto G, Pezzino S, Lempereur L, Calvagna R, et al. Protective effects of the sigma agonist Pre-084 in the rat retina. Br J Ophthalmol. 2007;91:1382-4 pubmed

Shin E, Nah S, Kim W, Ko K, Jhoo W, Lim Y, et al. The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan. Br J Pharmacol. 2005;144:908-18 pubmed

Brown C, Fezoui M, Selig W, Schwartz C, Ellis J. Antitussive activity of sigma-1 receptor agonists in the guinea-pig. Br J Pharmacol. 2004;141:233-40 pubmed