product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
BRL 37344, sodium salt
catalog :
0948
quantity :
10 mg (also 50 mg)
price :
184 USD
more info or order :
citations: 10
Reference |
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Maupoil V, Bronquard C, Freslon J, Cosnay P, Findlay I. Ectopic activity in the rat pulmonary vein can arise from simultaneous activation of alpha1- and beta1-adrenoceptors. Br J Pharmacol. 2007;150:899-905 pubmed
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Briones A, Daly C, Jiménez Altayó F, Martinez Revelles S, Gonzalez J, McGrath J, et al. Direct demonstration of beta1- and evidence against beta2- and beta3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. Br J Pharmacol. 2005;146:679-91 pubmed
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Brahmadevara N, Shaw A, Macdonald A. ALpha1-adrenoceptor antagonist properties of CGP 12177A and other beta-adrenoceptor ligands: evidence against beta(3)- or atypical beta-adrenoceptors in rat aorta. Br J Pharmacol. 2004;142:781-7 pubmed
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Cirino G, Sorrentino R, di Villa Bianca R, Popolo A, Palmieri A, Imbimbo C, et al. Involvement of beta 3-adrenergic receptor activation via cyclic GMP- but not NO-dependent mechanisms in human corpus cavernosum function. Proc Natl Acad Sci U S A. 2003;100:5531-6 pubmed
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Steinle J, Booz G, Meininger C, Day J, Granger H. Beta 3-adrenergic receptors regulate retinal endothelial cell migration and proliferation. J Biol Chem. 2003;278:20681-6 pubmed
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product information
brand :
Tocris
master code :
0948
SKU :
0948/10
product name :
BRL 37344, sodium salt
description :
3 agonist
target :
Adrenergic beta-3 Receptor Agonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
385.82
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent and selective 3 adrenoceptor agonist (Ki values are 287, 1750 and 1120 nM for 3, 1 and 2 receptors respectively).
catalog number base :
948
product keywords :
3-adrenoceptor b3-adrenoceptor agonists 3-adrenergic b3-adrenergic Receptors BRL37344 sodium salt GlaxoSmithKline GSK Adrenergic Beta-3 Receptors 0948,
extended description :
3 agonist
chemical name text :
(R*,R*)-( )-4-[2-[(2-(3-Chlorophenyl)-2-hydroxyethyl)amino]propyl]phenoxyacetic acid, sodium salt
formula :
C 19 H 21 NO 4 ClNa
formula text :
C19H21NO4ClNa
cas num :
127299-93-8
2020 USD :
176
2021 USD :
184 USD
storage :
Store at RT
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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