product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
NS 398
catalog :
0942
quantity :
10 mg (also 50 mg)
price :
191 USD
more info or order :
citations: 14
Reference |
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Messerschmidt L, Fischer S, Wiedemann P, Bringmann A, Hollborn M. Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation. Mol Vis. 2019;25:329-344 pubmed
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Sunters A, Armstrong V, Zaman G, Kypta R, Kawano Y, Lanyon L, et al. Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 r. J Biol Chem. 2010;285:8743-58 pubmed publisher
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Ray N, Bisher M, Enquist L. Cyclooxygenase-1 and -2 are required for production of infectious pseudorabies virus. J Virol. 2004;78:12964-74 pubmed
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product information
brand :
Tocris
master code :
0942
SKU :
0942/10
product name :
NS 398
description :
Cyclooxygenase-2 (COX-2) inhibitor
target :
Cyclooxygenase Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
314.36
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective cyclooxygenase-2 inhibitor (IC50 values are 3.8 and 100 u M for COX-2 and COX-1 respectively). Induces apoptosis in colorectal tumor cells and elevates COX-2 protein expression in vitro . Orally active and non-ulcerogenic analgesic and anti-inflammatory in vivo .
catalog number base :
942
product keywords :
Cyclooxygenase COX-2 inhibitors inhibits COX Oxygenases Oxidases NS398 Cyclooxygenase 0942,
extended description :
Cyclooxygenase-2 (COX-2) inhibitor
chemical name text :
N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide
formula :
C 13 H 18 N 2 O 5 S
formula text :
C13H18N2O5S
cas num :
123653-11-2
2020 USD :
185
2021 USD :
191 USD
storage :
Store at RT
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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