product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Fluoxetine hydrochloride
catalog :
0927
quantity :
10 mg (also 50 mg)
price :
98 USD
more info or order :
citations: 10
Reference
Kant R, Pasi S, Surolia A. Auto-Reactive Th17-Cells Trigger Obsessive-Compulsive-Disorder Like Behavior in Mice With Experimental Autoimmune Encephalomyelitis. Front Immunol. 2018;9:2508 pubmed publisher
Zhang X, Gaudry Q. Functional integration of a serotonergic neuron in the Drosophila antennal lobe. elife. 2016;5: pubmed publisher
Hooper C, Delaney C, Streeter T, Yarboro M, Poole S, Brown N, et al. Selective serotonin reuptake inhibitor exposure constricts the mouse ductus arteriosus in utero. Am J Physiol Heart Circ Physiol. 2016;311:H572-81 pubmed publisher
Sallin P, Jazwinska A. Acute stress is detrimental to heart regeneration in zebrafish. Open Biol. 2016;6: pubmed publisher
Pai V, Lemire J, Paré J, Lin G, Chen Y, Levin M. Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation. J Neurosci. 2015;35:4366-85 pubmed publisher
Silva B, Goles N, Varas R, Campusano J. Serotonin receptors expressed in Drosophila mushroom bodies differentially modulate larval locomotion. PLoS ONE. 2014;9:e89641 pubmed publisher
Stuart S, Butler P, Munafò M, Nutt D, Robinson E. A translational rodent assay of affective biases in depression and antidepressant therapy. Neuropsychopharmacology. 2013;38:1625-35 pubmed publisher
Kurita M, Holloway T, García Bea A, Kozlenkov A, Friedman A, Moreno J, et al. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity. Nat Neurosci. 2012;15:1245-54 pubmed publisher
Nozawa K, Kawabata Shoda E, Doihara H, Kojima R, Okada H, Mochizuki S, et al. TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells. Proc Natl Acad Sci U S A. 2009;106:3408-13 pubmed publisher
MacLean M, Deuchar G, Hicks M, Morecroft I, Shen S, Sheward J, et al. Overexpression of the 5-hydroxytryptamine transporter gene: effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension. Circulation. 2004;109:2150-5 pubmed
product information
brand :
Tocris
master code :
0927
SKU :
0927/10
product name :
Fluoxetine hydrochloride
description :
5-HT reuptake inhibitor
target :
5-HT Transporter Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
345.78
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective serotonin reuptake inhibitor. Binds to the human 5-HT transporter with a Ki of 0.9 nmol/l and is between 150- and 900- fold selective over 5-HT1A, 5-HT2A, H1, 1, 2-adrenergic, and muscarinic receptors. Antidepressant. Induces differentiation of neuronal precursors, enhancing neuronal characteristics.
catalog number base :
927
product keywords :
5-HT reuptake inhibitors inhibits Serotonin Transporters SERT 5-Hydroxytryptamine Monoamine Neurotransmitter 5-HT Transporters Neural Stem Cells 0927,
extended description :
5-HT reuptake inhibitor
chemical name text :
N-Methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenylpropylamine hydrochloride
formula :
C 17 H 18 F 3 NO.HCl
formula text :
C17H18F3NO.HCl
cas num :
56296-78-7
2020 USD :
94
2021 USD :
98 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK