This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
beta-Funaltrexamine hydrochloride
catalog :
0926
quantity :
10 mg (also 50 mg)
price :
221 USD
citations: 7
Reference
Crowley R, Riley A, Alder A, Anderson R, Luo D, Kaska S, et al. Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Design, Synthesis, and Evaluation of Analogues with Improved Potency and G-protein Activation Bias at the μ-Opioid Receptor. ACS Chem Neurosci. 2020;11:1781-1790 pubmed publisher
Chen C, Lu M, Pan Q, Fichna J, Zheng L, Wang K, et al. Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner. PLoS ONE. 2015;10:e0145556 pubmed publisher
Romero Picó A, Vazquez M, González Touceda D, Folgueira C, Skibicka K, Alvarez Crespo M, et al. Hypothalamic ?-opioid receptor modulates the orexigenic effect of ghrelin. Neuropsychopharmacology. 2013;38:1296-307 pubmed publisher
Phillips R, Cleary D, Nalwalk J, Arttamangkul S, Hough L, Heinricher M. Pain-facilitating medullary neurons contribute to opioid-induced respiratory depression. J Neurophysiol. 2012;108:2393-404 pubmed publisher
Tzeng T, Liou S, Liu I. Myricetin Ameliorates Defective Post-Receptor Insulin Signaling via ?-Endorphin Signaling in the Skeletal Muscles of Fructose-Fed Rats. Evid Based Complement Alternat Med. 2011;2011:150752 pubmed publisher
Largent Milnes T, Yamamoto T, Nair P, Moulton J, Hruby V, Lai J, et al. Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance. Br J Pharmacol. 2010;161:986-1001 pubmed publisher
Cecchi M, Capriles N, Watson S, Akil H. Differential responses to morphine-induced analgesia in the tail-flick test. Behav Brain Res. 2008;194:146-51 pubmed publisher
product information
brand :
Tocris
master code :
0926
SKU :
0926/10
product name :
beta-Funaltrexamine hydrochloride
description :
Irreversible and selective antagonist
target :
mu Opioid Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
490.99
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective u opioid receptor antagonist.
catalog number base :
926
product keywords :
Irreversible -opioid mu-opioid selective antagonists MOP Receptors OP3 -Funaltrexamine beta-Funaltrexamine hydrochloride -FNA beta-FNA b-FNA Mu Opioid Receptors 0926,
extended description :
Irreversible and selective antagonist
chemical name text :
(E)-4-[[5 ,6 )-17-Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]amino]-4-oxo-2-butenoicacid methyl ester hydrochloride
formula :
C 25 H 30 N 2 O 6 .HCl
formula text :
C25H30N2O6.HCl
cas num :
72786-10-8
2020 USD :
214
2021 USD :
221 USD
alt names :
-FNA
storage :
Store at -20°C
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK