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company name :
Tocris Bioscience
product type :
chemical
product name :
0922/100
catalog :
0922/100
quantity :
100 mg
price :
211 USD
more info or order :
citations: 20
Reference
Mitlöhner J, Kaushik R, Niekisch H, Blondiaux A, Gee C, Happel M, et al. Dopamine Receptor Activation Modulates the Integrity of the Perisynaptic Extracellular Matrix at Excitatory Synapses. Cells. 2020;9: pubmed publisher
Zhang S, Yang J, Reinach P, Wang F, Zhang L, Fan M, et al. Dopamine Receptor Subtypes Mediate Opposing Effects on Form Deprivation Myopia in Pigmented Guinea Pigs. Invest Ophthalmol Vis Sci. 2018;59:4441-4448 pubmed publisher
Zike I, Chohan M, Kopelman J, Krasnow E, Flicker D, Nautiyal K, et al. OCD candidate gene SLC1A1/EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior. Proc Natl Acad Sci U S A. 2017;114:5719-5724 pubmed publisher
Grochowska K, Yuanxiang P, Bar J, Raman R, Brugal G, Sahu G, et al. Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction. EMBO Rep. 2017;18:962-981 pubmed publisher
Mi G, Liu S, Zhang J, Liang H, Gao Y, Li N, et al. Levo-Tetrahydroberberrubine Produces Anxiolytic-Like Effects in Mice through the 5-HT1A Receptor. PLoS ONE. 2017;12:e0168964 pubmed publisher
Toro C, Trapani J, Pacentine I, Maeda R, SHEETS L, Mo W, et al. Dopamine Modulates the Activity of Sensory Hair Cells. J Neurosci. 2015;35:16494-503 pubmed publisher
Polito M, Guiot E, Gangarossa G, Longueville S, Doulazmi M, Valjent E, et al. Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32(1,2,3). Eneuro. 2015;2: pubmed publisher
Xing L, McDonald H, Da Fonte D, Gutierrez Villagomez J, Trudeau V. Dopamine D1 receptor activation regulates the expression of the estrogen synthesis gene aromatase B in radial glial cells. Front Neurosci. 2015;9:310 pubmed publisher
Tozzi A, de Iure A, Tantucci M, Durante V, Quiroga Varela A, Giampà C, et al. Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system. Front Cell Neurosci. 2015;9:192 pubmed publisher
Mikulak J, Bozzo L, Roberto A, Pontarini E, Tentorio P, Hudspeth K, et al. Dopamine inhibits the effector functions of activated NK cells via the upregulation of the D5 receptor. J Immunol. 2014;193:2792-800 pubmed publisher
Moreno E, Moreno Delgado D, Navarro G, Hoffmann H, Fuentes S, Rosell Vilar S, et al. Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: ?1-D1-H3 receptor complexes as key targets for reducing cocaine's effects. J Neurosci. 2014;34:3545-58 pubmed publisher
Murugan M, Harward S, Scharff C, Mooney R. Diminished FoxP2 levels affect dopaminergic modulation of corticostriatal signaling important to song variability. Neuron. 2013;80:1464-76 pubmed publisher
Jia J, Zhao J, Hu Z, Lindberg D, Li Z. Age-dependent regulation of synaptic connections by dopamine D2 receptors. Nat Neurosci. 2013;16:1627-36 pubmed publisher
Cilz N, Kurada L, Hu B, Lei S. Dopaminergic modulation of GABAergic transmission in the entorhinal cortex: concerted roles of α1 adrenoreceptors, inward rectifier K⁺, and T-type Ca²⁺ channels. Cereb Cortex. 2014;24:3195-208 pubmed publisher
Prado C, Contreras F, Gonzalez H, Diaz P, Elgueta D, Barrientos M, et al. Stimulation of dopamine receptor D5 expressed on dendritic cells potentiates Th17-mediated immunity. J Immunol. 2012;188:3062-70 pubmed publisher
Van Hook M, Wong K, Berson D. Dopaminergic modulation of ganglion-cell photoreceptors in rat. Eur J Neurosci. 2012;35:507-18 pubmed publisher
Herwerth M, Jensen V, Novak M, Konopka W, Hvalby O, Köhr G. D4 dopamine receptors modulate NR2B NMDA receptors and LTP in stratum oriens of hippocampal CA1. Cereb Cortex. 2012;22:1786-98 pubmed publisher
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Marcellino D, Ferre S, Casado V, Cortes A, Le Foll B, Mazzola C, et al. Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum. J Biol Chem. 2008;283:26016-25 pubmed publisher
Stramiello M, Wagner J. D1/5 receptor-mediated enhancement of LTP requires PKA, Src family kinases, and NR2B-containing NMDARs. Neuropharmacology. 2008;55:871-7 pubmed publisher
product information
master code :
922
SKU :
0922/100
product name :
SKF 38393 hydrobromide
unit size :
100 mg
description :
Selective D1-like agonist
target :
Dopamine D1 and D5 Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
336.23
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SKF 38393 hydrobromide is a prototypical D1-like dopamine receptor selective partial agonist (Ki values are 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D1, D5, D2, D3 and D4 receptors respectively).
top caption :
Selective D1-like agonist
extended description :
Selective D1-like agonist
chemical name text :
( )-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide
formula :
C16H17NO2.HBr
formula text :
C16H17NO2.HBr
cas num :
20012-10-6
USD :
211 USD
product details :
Selective D1-like agonist
storage :
Desiccate at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK