AIDA | Tocris Bioscience 0904 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AIDA

catalog :

0904

quantity :

10 mg (also 50 mg)

price :

195 USD

more info or order :

Tocris Bioscience product webpage

citations: 9

Reference
Saitoh F, Wakatsuki S, Tokunaga S, Fujieda H, Araki T. Glutamate signals through mGluR2 to control Schwann cell differentiation and proliferation. Sci Rep. 2016;6:29856 pubmed publisher
Ady V, Perroy J, Tricoire L, Piochon C, Dadak S, Chen X, et al. Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 delta glutamate receptors. EMBO Rep. 2014;15:103-9 pubmed publisher
De May C, Ali A. Cell type-specific regulation of inhibition via cannabinoid type 1 receptors in rat neocortex. J Neurophysiol. 2013;109:216-24 pubmed publisher
Mahler S, Hensley Simon M, Tahsili Fahadan P, Lalumiere R, Thomas C, Fallon R, et al. Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors. Addict Biol. 2014;19:49-60 pubmed publisher
Cassé F, Bardou I, Danglot L, Briens A, Montagne A, Parcq J, et al. Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. J Neurosci. 2012;32:5186-99 pubmed publisher
Wibrand K, Panja D, Tiron A, Ofte M, Skaftnesmo K, Lee C, et al. Differential regulation of mature and precursor microRNA expression by NMDA and metabotropic glutamate receptor activation during LTP in the adult dentate gyrus in vivo. Eur J Neurosci. 2010;31:636-45 pubmed publisher
Shin J, Kim Y, Linden D. Dendritic glutamate release produces autocrine activation of mGluR1 in cerebellar Purkinje cells. Proc Natl Acad Sci U S A. 2008;105:746-50 pubmed publisher
Pan Y, Berman Y, Carr K. Effects of the group I metabotropic glutamate receptor agonist, DHPG, and injection stress on striatal cell signaling in food-restricted and ad libitum fed rats. BMC Neurosci. 2004;5:50 pubmed
Yeckel M, Kapur A, Johnston D. Multiple forms of LTP in hippocampal CA3 neurons use a common postsynaptic mechanism. Nat Neurosci. 1999;2:625-33 pubmed

product information

brand :

Tocris

master code :

0904

SKU :

0904/10

product name :

AIDA

description :

Potent and selective group I mGlu antagonist

target :

Group I mGluR Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

221.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

A relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a), having no effect on group II (mGlu2) or group III (mGlu4) receptors expressed individually in baby hamster kidney cells. Has no effect on ionotropic glutamate receptors. Centrally active following systemic administration in vivo .

catalog number base :

904

product keywords :

Potent selective group I antagonist Group Receptors mGlu1 mGlu5 mGluR1 mGluR5 Glutamate Metabotropic UPF523 UPF 523 Glutamate (Metabotropic) Group I Receptors 0904,

extended description :

Potent and selective group I mGlu antagonist

chemical name text :

(RS)-1-Aminoindan-1,5-dicarboxylic acid

formula :

C 11 H 11 NO 4

formula text :

C11H11NO4

cas num :

168560-79-0

2020 USD :

187

2021 USD :

195 USD

alt names :

UPF 523

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage