0904/10 | Tocris Bioscience 0904/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0904/10

catalog :

0904/10

quantity :

10 mg (also 50 mg)

price :

246 USD

more info or order :

Tocris Bioscience product webpage

citations: 10

Reference
Saitoh F, Wakatsuki S, Tokunaga S, Fujieda H, Araki T. Glutamate signals through mGluR2 to control Schwann cell differentiation and proliferation. Sci Rep. 2016;6:29856 pubmed publisher
Ady V, Perroy J, Tricoire L, Piochon C, Dadak S, Chen X, et al. Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 delta glutamate receptors. EMBO Rep. 2014;15:103-9 pubmed publisher
De May C, Ali A. Cell type-specific regulation of inhibition via cannabinoid type 1 receptors in rat neocortex. J Neurophysiol. 2013;109:216-24 pubmed publisher
Mahler S, Hensley Simon M, Tahsili Fahadan P, Lalumiere R, Thomas C, Fallon R, et al. Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors. Addict Biol. 2014;19:49-60 pubmed publisher
Cassé F, Bardou I, Danglot L, Briens A, Montagne A, Parcq J, et al. Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. J Neurosci. 2012;32:5186-99 pubmed publisher
Sun L, Gu L, Wang S, Yuan J, Yang H, Zhu J, et al. N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity. PLoS ONE. 2012;7:e32503 pubmed publisher
Wibrand K, Panja D, Tiron A, Ofte M, Skaftnesmo K, Lee C, et al. Differential regulation of mature and precursor microRNA expression by NMDA and metabotropic glutamate receptor activation during LTP in the adult dentate gyrus in vivo. Eur J Neurosci. 2010;31:636-45 pubmed publisher
Shin J, Kim Y, Linden D. Dendritic glutamate release produces autocrine activation of mGluR1 in cerebellar Purkinje cells. Proc Natl Acad Sci U S A. 2008;105:746-50 pubmed publisher
Pan Y, Berman Y, Carr K. Effects of the group I metabotropic glutamate receptor agonist, DHPG, and injection stress on striatal cell signaling in food-restricted and ad libitum fed rats. BMC Neurosci. 2004;5:50 pubmed
Yeckel M, Kapur A, Johnston D. Multiple forms of LTP in hippocampal CA3 neurons use a common postsynaptic mechanism. Nat Neurosci. 1999;2:625-33 pubmed

product information

master code :

904

SKU :

0904/10

product name :

AIDA

unit size :

10 mg (also 50 mg)

description :

Potent and selective group I mGlu antagonist

target :

Group I mGluR Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

221.21

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AIDA is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a), having no effect on group II (mGlu2) or group III (mGlu4) receptors expressed individually in baby hamster kidney cells. Has no effect on ionotropic glutamate receptors. Centrally active following systemic administration in vivo .

top caption :

Potent and selective group I mGlu antagonist

extended description :

Potent and selective group I mGlu antagonist

chemical name text :

(RS)-1-Aminoindan-1,5-dicarboxylic acid

formula :

C11H11NO4

formula text :

C11H11NO4

cas num :

168560-79-0

USD :

246 USD

product details :

Potent and selective group I mGlu antagonist

alt names :

UPF 523

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage