This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
Cimetidine
catalog :
0902/100
quantity :
100 mg
price :
81 USD
citations: 8
Reference
Femenía T, Magara S, DuPont C, Lindskog M. Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression. Int J Neuropsychopharmacol. 2015;18: pubmed publisher
Wang Y, Jiang Y, Ikeda J, Tian T, Sato A, Ohtsu H, et al. Roles of histamine on the expression of aldehyde dehydrogenase 1 in endometrioid adenocarcinoma cell line. Cancer Med. 2014;3:1126-35 pubmed publisher
Kurtz K, Moor A, Souza Smith F, Breslin J. Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics. Microcirculation. 2014;21:593-605 pubmed publisher
Francis H, Demorrow S, Venter J, Onori P, White M, Gaudio E, et al. Inhibition of histidine decarboxylase ablates the autocrine tumorigenic effects of histamine in human cholangiocarcinoma. Gut. 2012;61:753-64 pubmed publisher
Connelly W, Shenton F, Lethbridge N, Leurs R, Waldvogel H, Faull R, et al. The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS. Br J Pharmacol. 2009;157:55-63 pubmed publisher
Hough L, Nalwalk J, Phillips J, Kern B, Shan Z, Wentland M, et al. CC12, a high-affinity ligand for [3H]cimetidine binding, is an improgan antagonist. Neuropharmacology. 2007;52:1244-55 pubmed
Andre N, Cherouati N, Prual C, Steffan T, Zeder Lutz G, Magnin T, et al. Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen. Protein Sci. 2006;15:1115-26 pubmed
Strait R, Morris S, Finkelman F. IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking. J Clin Invest. 2006;116:833-41 pubmed
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
0902
SKU :
0902/100
product name :
Cimetidine
description :
H2 antagonist, I1 agonist
target :
Histamine H2 Receptor Antagonists
unit size :
100 mg
category :
Small Molecules
purity :
99%
storage :
Store at RT
observed molecular weight :
252.34
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Cimetidine is a widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand.
product keywords :
I1 agonists histamine H2 antagonists inverse Imidazoline Receptors histaminergic Histamine H2 Receptors I1 Receptors 0902,
extended description :
H2 antagonist, I1 agonist
chemical name text :
N-Cyano-N -methyl-N -[2-[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine
formula :
C10H16N6S
formula text :
C10H16N6S
cas num :
51481-61-9
USD :
89
USD 2025 :
81 USD
product details :
H2 antagonist, I1 agonist
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK