product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Dihydrexidine hydrochloride
catalog :
0884
quantity :
25 mg
price :
675 USD
more info or order :
citations: 4
Reference
Parker M, Vander Kooi C. Microplate-based screening for small molecule inhibitors of neuropilin-2/vascular endothelial growth factor-C interactions. Anal Biochem. 2014;453:4-6 pubmed publisher
Urizar E, Yano H, Kolster R, Gales C, Lambert N, Javitch J. CODA-RET reveals functional selectivity as a result of GPCR heteromerization. Nat Chem Biol. 2011;7:624-30 pubmed publisher
Smith W, Starck S, Roberts R, Schuman E. Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons. Neuron. 2005;45:765-79 pubmed
Gorelova N, Seamans J, Yang C. Mechanisms of dopamine activation of fast-spiking interneurons that exert inhibition in rat prefrontal cortex. J Neurophysiol. 2002;88:3150-66 pubmed
product information
brand :
Tocris
master code :
0884
SKU :
0884/25
product name :
Dihydrexidine hydrochloride
description :
Selective D1-like agonist
target :
Dopamine D1 and D5 Receptor Agonists
category :
Small Molecules
unit size :
25 mg
purity :
98%
observed molecular weight :
303.79
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
A potent, full efficacy dopamine D1 agonist which shows no agonist activity at peripheral D2 receptors or adrenoceptors at doses which cause maximal stimulation of D1 sites. The compound appears to be fully bioavailable in brain and exhibits profound antiparkinsonism effects in vivo .
catalog number base :
884
product keywords :
Selective D1-like agonists Dopamine Receptors D5 dopaminergic D1 and D5 Receptors 0884,
extended description :
Selective D1-like agonist
chemical name text :
( )-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride
formula :
C 17 H 17 NO 2 .HCl
formula text :
C17H17NO2.HCl
cas num :
158704-02-0
2020 USD :
661
2021 USD :
675 USD
storage :
Desiccate at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK