product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0880/10
catalog :
0880/10
quantity :
10 mg (also 50 mg)
price :
146 USD
more info or order :
citations: 45
Reference |
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Padovan Neto F, Sammut S, Chakroborty S, Dec A, Threlfell S, Campbell P, et al. Facilitation of corticostriatal transmission following pharmacological inhibition of striatal phosphodiesterase 10A: role of nitric oxide-soluble guanylyl cyclase-cGMP signaling pathways. J Neurosci. 2015;35:5781-91 pubmed publisher
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Makara J, Katona I, Nyiri G, Németh B, Ledent C, Watanabe M, et al. Involvement of nitric oxide in depolarization-induced suppression of inhibition in hippocampal pyramidal cells during activation of cholinergic receptors. J Neurosci. 2007;27:10211-22 pubmed
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Newman Z, Malik P, Wu T, Ochoa C, Watsa N, Lindgren C. Endocannabinoids mediate muscarine-induced synaptic depression at the vertebrate neuromuscular junction. Eur J Neurosci. 2007;25:1619-30 pubmed
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Yang S, Cox C. Modulation of inhibitory activity by nitric oxide in the thalamus. J Neurophysiol. 2007;97:3386-95 pubmed
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Dalsgaard T, Simonsen U, Fago A. Nitrite-dependent vasodilation is facilitated by hypoxia and is independent of known NO-generating nitrite reductase activities. Am J Physiol Heart Circ Physiol. 2007;292:H3072-8 pubmed
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Anselm E, Chataigneau M, Ndiaye M, Chataigneau T, Schini Kerth V. Grape juice causes endothelium-dependent relaxation via a redox-sensitive Src- and Akt-dependent activation of eNOS. Cardiovasc Res. 2007;73:404-13 pubmed
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Agren P, Cogolludo A, Kessels C, Perez Vizcaino F, De Mey J, Blanco C, et al. Ontogeny of chicken ductus arteriosus response to oxygen and vasoconstrictors. Am J Physiol Regul Integr Comp Physiol. 2007;292:R485-96 pubmed
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Cauwels A, Janssen B, Buys E, Sips P, Brouckaert P. Anaphylactic shock depends on PI3K and eNOS-derived NO. J Clin Invest. 2006;116:2244-51 pubmed
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McNeish A, Sandow S, Neylon C, Chen M, Dora K, Garland C. Evidence for involvement of both IKCa and SKCa channels in hyperpolarizing responses of the rat middle cerebral artery. Stroke. 2006;37:1277-82 pubmed
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Namkoong S, Lee S, Kim C, Kim Y, Chung H, Lee H, et al. Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells. Exp Mol Med. 2005;37:588-600 pubmed
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Sachs D, Cunha F, Ferreira S. Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway. Proc Natl Acad Sci U S A. 2004;101:3680-5 pubmed
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Cirino G, Sorrentino R, di Villa Bianca R, Popolo A, Palmieri A, Imbimbo C, et al. Involvement of beta 3-adrenergic receptor activation via cyclic GMP- but not NO-dependent mechanisms in human corpus cavernosum function. Proc Natl Acad Sci U S A. 2003;100:5531-6 pubmed
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Tsang S, Yao X, Wong C, Au C, Chen Z, Huang Y. Contribution of Na+ -Ca2+ exchanger to pinacidil-induced relaxation in the rat mesenteric artery. Br J Pharmacol. 2003;138:453-60 pubmed
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Bellamy T, Garthwaite J. Pharmacology of the nitric oxide receptor, soluble guanylyl cyclase, in cerebellar cells. Br J Pharmacol. 2002;136:95-103 pubmed
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Villamor E, Ruijtenbeek K, Pulgar V, De Mey J, Blanco C. Vascular reactivity in intrapulmonary arteries of chicken embryos during transition to ex ovo life. Am J Physiol Regul Integr Comp Physiol. 2002;282:R917-27 pubmed
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Stanford S, Gitlin J, Mitchell J. Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat. Br J Pharmacol. 2001;133:825-32 pubmed
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Casado M, Dieudonne S, Ascher P. Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse. Proc Natl Acad Sci U S A. 2000;97:11593-7 pubmed
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Haynes J. A(2A) adenosine receptor mediated potassium channel activation in rat epididymal smooth muscle. Br J Pharmacol. 2000;130:685-91 pubmed
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Mundey M, Jonas M, Worthley T, Scholefield J, Wilson V. Pharmacological characterization of neurogenic responses of the sheep isolated internal anal sphincter. Br J Pharmacol. 2000;130:489-94 pubmed
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Hedlund P, Aszodi A, Pfeifer A, Alm P, Hofmann F, Ahmad M, et al. Erectile dysfunction in cyclic GMP-dependent kinase I-deficient mice. Proc Natl Acad Sci U S A. 2000;97:2349-54 pubmed
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Dick J, Van Geldre L, Timmermans J, Lefebvre R. Investigation of the interaction between nitric oxide and vasoactive intestinal polypeptide in the guinea-pig gastric fundus. Br J Pharmacol. 2000;129:751-63 pubmed
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Perez Vizcaino F, Cogolludo A, Zaragozá Arnáez F, Fajardo S, Ibarra M, López López J, et al. Vasodilator effects of sodium nitroprusside, levcromakalim and their combination in isolated rat aorta. Br J Pharmacol. 1999;128:1419-26 pubmed
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Villarroya M, Herrero C, Ruiz Nuño A, de Pascual R, del Valle M, Michelena P, et al. PF9404C, a new slow NO donor with beta receptor blocking properties. Br J Pharmacol. 1999;128:1713-22 pubmed
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Rach C, Gandhi M, Docherty J, Finegan B, Clanachan A. Deficiency in myocardial NO biosignalling after cardioplegic arrest: mechanisms and contribution to post-storage mechanical dysfunction. Br J Pharmacol. 1999;128:891-902 pubmed
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Cogolludo A, Perez Vizcaino F, Fajardo S, Ibarra M, Tamargo J. Effects of nicorandil as compared to mixtures of sodium nitroprusside and levcromakalim in isolated rat aorta. Br J Pharmacol. 1999;126:1025-33 pubmed
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product information
master code :
880
SKU :
0880/10
product name :
ODQ
unit size :
10 mg (also 50 mg)
description :
Selective inhibitor of NO-sensitive guanylyl cyclase
target :
Additional NOS Inhibitors
category :
Small Molecules
purity :
99%
observed molecular weight :
187.16
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ODQ is a potent and selective inhibitor of NO-sensitive guanylyl cyclase.
top caption :
Selective inhibitor of NO-sensitive guanylyl cyclase
extended description :
Selective inhibitor of NO-sensitive guanylyl cyclase
chemical name text :
1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one
formula :
C9H5N3O2
formula text :
C9H5N3O2
cas num :
41443-28-1
USD :
146 USD
product details :
Selective inhibitor of NO-sensitive guanylyl cyclase
storage :
Desiccate at +4░C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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