Evans Blue tetrasodium salt | Tocris Bioscience 0845 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Evans Blue tetrasodium salt

catalog :

0845

quantity :

1 g

price :

73 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Uderhardt S, Martins A, Tsang J, Lämmermann T, Germain R. Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell. 2019;177:541-555.e17 pubmed publisher
Gao J, Xin W, Huang J, Ji B, Gao S, Chen L, et al. Research articleHemolysis in human erythrocytes by Clostridium perfringens epsilon toxin requires activation of P2 receptors. Virulence. 2018;9:1601-1614 pubmed publisher

product information

brand :

Tocris

master code :

0845

SKU :

0845/1G

product name :

Evans Blue tetrasodium salt

description :

Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist

target :

Glutamate (EAAT) Transporter Inhibitors

category :

Small Molecules

unit size :

1 g

purity :

90%

observed molecular weight :

960.82

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent inhibitor of L-glutamate uptake into synaptic vesicles. Also inhibits AMPA and kainate receptor-mediated currents (IC50 values are 220 and 150 nM respectively). P2X-selective purinoceptor antagonist. Also a non-permeating dye, stains damaged plasma membrane and enters in the cytoplasm and nucleus, used for checking cell viability.

catalog number base :

845

product keywords :

AMPA/kainate antagonist Potent inhibitors inhibits L-glutamate reuptake into synaptic vesicles Selective P2X purinergic purinoceptors Glutamate AMPA Receptors iGluR Ionotropic Kainate EAAT Excitatory Amino Acid Transporters GLAST GLT-1 Monoamine Neurotran Glutamate Transporters AMPA Receptors P2X Receptors Kainate Receptors Labels and Stains Fluorescent Transporter Probes 0845,

extended description :

Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist

chemical name text :

6,6-[(3,3 -Dimethyl[1,1 -biphenyl]-4,4 -diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt

formula :

C 34 H 24 N 6 Na 4 O 14 S 4

formula text :

C34H24N6Na4O14S4

cas num :

314-13-6

2020 USD :

2021 USD :

73 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage