0845/1G | Tocris Bioscience 0845/1G product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0845/1G

catalog :

0845/1G

quantity :

1 g

price :

84 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Uderhardt S, Martins A, Tsang J, Lämmermann T, Germain R. Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell. 2019;177:541-555.e17 pubmed publisher
Gao J, Xin W, Huang J, Ji B, Gao S, Chen L, et al. Research articleHemolysis in human erythrocytes by Clostridium perfringens epsilon toxin requires activation of P2 receptors. Virulence. 2018;9:1601-1614 pubmed publisher
Nakazato R, Kawabe K, Yamada D, Ikeno S, Mieda M, Shimba S, et al. Disruption of Bmal1 Impairs Blood-Brain Barrier Integrity via Pericyte Dysfunction. J Neurosci. 2017;37:10052-10062 pubmed publisher

product information

master code :

845

SKU :

0845/1G

product name :

Evans Blue tetrasodium salt

unit size :

1 g

description :

Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist

target :

Glutamate (EAAT) Transporter Inhibitors

category :

Small Molecules

purity :

90%

observed molecular weight :

960.82

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Evans Blue tetrasodium salt is a potent inhibitor of L-glutamate uptake into synaptic vesicles. Also inhibits AMPA and kainate receptor-mediated currents (IC50 values are 220 and 150 nM respectively). P2X-selective purinoceptor antagonist. Also a non-permeating dye, stains damaged plasma membrane and enters in the cytoplasm and nucleus, used for checking cell viability.

top caption :

Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist

extended description :

Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist

chemical name text :

6,6-[(3,3 -Dimethyl[1,1 -biphenyl]-4,4 -diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt

formula :

C34H24N6Na4O14S4

formula text :

C34H24N6Na4O14S4

cas num :

314-13-6

USD :

84 USD

product details :

Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage