product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
(S)-3,5-DHPG
catalog :
0805
quantity :
10 mg
price :
300 USD
more info or order :
citations: 37
Reference |
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Nakamoto M, Nalavadi V, Epstein M, Narayanan U, Bassell G, Warren S. Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc Natl Acad Sci U S A. 2007;104:15537-42 pubmed
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Fukunaga I, Yeo C, Batchelor A. Potent and specific action of the mGlu1 antagonists YM-298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices. Br J Pharmacol. 2007;151:870-6 pubmed
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Westmark C, Malter J. FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol. 2007;5:e52 pubmed
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Xu W, Wong T, Chery N, Gaertner T, Wang Y, Baudry M. Calpain-mediated mGluR1alpha truncation: a key step in excitotoxicity. Neuron. 2007;53:399-412 pubmed
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Ruangkittisakul A, Schwarzacher S, Secchia L, Poon B, Ma Y, Funk G, et al. High sensitivity to neuromodulator-activated signaling pathways at physiological [K+] of confocally imaged respiratory center neurons in on-line-calibrated newborn rat brainstem slices. J Neurosci. 2006;26:11870-80 pubmed
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El Kouhen O, Lehto S, Pan J, Chang R, Baker S, Zhong C, et al. Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist. Br J Pharmacol. 2006;149:761-74 pubmed
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Kuang D, Yao Y, MacLean D, Wang M, Hampson D, Chang B. Ancestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptors. Proc Natl Acad Sci U S A. 2006;103:14050-5 pubmed
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Jung K, Mangieri R, Stapleton C, Kim J, Fegley D, Wallace M, et al. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. Mol Pharmacol. 2005;68:1196-202 pubmed
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Jacob S, Choe C, Uhlen P, Degray B, Yeckel M, Ehrlich B. Signaling microdomains regulate inositol 1,4,5-trisphosphate-mediated intracellular calcium transients in cultured neurons. J Neurosci. 2005;25:2853-64 pubmed
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Wu M, Hajszan T, Xu C, Leranth C, Alreja M. Group I metabotropic glutamate receptor activation produces a direct excitation of identified septohippocampal cholinergic neurons. J Neurophysiol. 2004;92:1216-25 pubmed
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Cai W, Hisatsune C, Nakamura K, Nakamura T, Inoue T, Mikoshiba K. Activity-dependent expression of inositol 1,4,5-trisphosphate receptor type 1 in hippocampal neurons. J Biol Chem. 2004;279:23691-8 pubmed
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Paladini C, Robinson S, Morikawa H, Williams J, Palmiter R. Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism. Proc Natl Acad Sci U S A. 2003;100:2866-71 pubmed
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product information
brand :
Tocris
master code :
0805
SKU :
0805/10
product name :
(S)-3,5-DHPG
description :
Selective group I mGlu agonist; active enantiomer of 3,5-DHPG (Cat. No. 0342)
target :
Group I mGluR Agonists
category :
Small Molecules
unit size :
10 mg
purity :
98%
observed molecular weight :
183.16
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective group I mGlu receptor agonist. . Racemate also available.
catalog number base :
805
product keywords :
Selective group I agonists Active enantiomer Group Receptors mGlu1 mGlu5 mGluR1 mGluR5 Glutamate Metabotropic Glutamate (Metabotropic) Group I Receptors 0805,
extended description :
Selective group I mGlu agonist; active enantiomer of 3,5-DHPG (Cat. No. 0342)
chemical name text :
(S)-3,5-Dihydroxyphenylglycine
formula :
C 8 H 9 NO 4
formula text :
C8H9NO4
cas num :
162870-29-3
2020 USD :
285
2021 USD :
300 USD
storage :
Desiccate at -20°C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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