MSOP | Tocris Bioscience 0803 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MSOP

catalog :

0803

quantity :

25 mg

price :

432 USD

more info or order :

Tocris Bioscience product webpage

citations: 7

Reference
Spaziano G, Luongo L, Guida F, Petrosino S, Matteis M, Palazzo E, et al. Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS. Biomed Res Int. 2015;2015:980983 pubmed publisher
Liu M, Kang S, Shi T, Koga K, Zhang M, Collingridge G, et al. Long-term potentiation of synaptic transmission in the adult mouse insular cortex: multielectrode array recordings. J Neurophysiol. 2013;110:505-21 pubmed publisher
Ster J, Mateos J, Grewe B, Coiret G, Corti C, Corsi M, et al. Enhancement of CA3 hippocampal network activity by activation of group II metabotropic glutamate receptors. Proc Natl Acad Sci U S A. 2011;108:9993-7 pubmed publisher
Derbenev A, Monroe M, Glatzer N, Smith B. Vanilloid-mediated heterosynaptic facilitation of inhibitory synaptic input to neurons of the rat dorsal motor nucleus of the vagus. J Neurosci. 2006;26:9666-72 pubmed
Browning K, Zheng Z, Gettys T, Travagli R. Vagal afferent control of opioidergic effects in rat brainstem circuits. J Physiol. 2006;575:761-76 pubmed
Jiang Q, Yan Z, Feng J. Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism. J Neurosci. 2006;26:4318-28 pubmed
Melyan Z, Lancaster B, Wheal H. Metabotropic regulation of intrinsic excitability by synaptic activation of kainate receptors. J Neurosci. 2004;24:4530-4 pubmed

product information

brand :

Tocris

master code :

0803

SKU :

0803/25

product name :

MSOP

description :

Specific group III mGlu antagonist

target :

Group III mGluR Antagonists

category :

Small Molecules

unit size :

25 mg

observed molecular weight :

199.1

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective group III metabotropic glutamate receptor antagonist. Displays an apparent KD of 51 u M for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to 700 u M for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. Has no activity on postsynaptic mGlu receptors or on ionotropic glutamate receptors on neonatal rat motoneurons.

catalog number base :

803

product keywords :

Specific group III mGlur antagonists Group Receptors mGlu4 mGlu6 mGlu7 mGlu8 mGluR4 mGluR6 mGluR7 mGluR8 Glutamate Metabotropic Glutamate (Metabotropic) Group III Receptors 0803,

extended description :

Specific group III mGlu antagonist

chemical name text :

(RS)- -Methylserine-O-phosphate

formula :

C 4 H 10 NO 6 P

formula text :

C4H10NO6P

cas num :

66515-29-5

2020 USD :

415

2021 USD :

432 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage