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company name :
Tocris Bioscience
product type :
chemical
product name :
0764/10
catalog :
0764/10
quantity :
10 mg (also 50 mg)
price :
292 USD
more info or order :
citations: 19
Reference
Robins M, Chiang T, Mores K, Alongkronrusmee D, van Rijn R. Critical Role for Gi/o-Protein Activity in the Dorsal Striatum in the Reduction of Voluntary Alcohol Intake in C57Bl/6 Mice. Front Psychiatry. 2018;9:112 pubmed publisher
Wang D, Tawfik V, Corder G, Low S, Francois A, Basbaum A, et al. Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits. Neuron. 2018;98:90-108.e5 pubmed publisher
Ye Y, Bernabé D, Salvo E, Viet C, Ono K, Dolan J, et al. Alterations in opioid inhibition cause widespread nociception but do not affect anxiety-like behavior in oral cancer mice. Neuroscience. 2017;363:50-61 pubmed publisher
Levoye A, Zwier J, Jaracz Ros A, Klipfel L, Cottet M, Maurel D, et al. A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate. Front Endocrinol (Lausanne). 2015;6:167 pubmed publisher
Neumann C, Bigliardi Qi M, Widmann C, Bigliardi P. The δ-opioid receptor affects epidermal homeostasis via ERK-dependent inhibition of transcription factor POU2F3. J Invest Dermatol. 2015;135:471-480 pubmed publisher
Schuster D, Metcalf M, Kitto K, Messing R, Fairbanks C, Wilcox G. Ligand requirements for involvement of PKC? in synergistic analgesic interactions between spinal ? and ? opioid receptors. Br J Pharmacol. 2015;172:642-53 pubmed publisher
Ong E, Xue L, Olmstead M, Cahill C. Prolonged morphine treatment alters ? opioid receptor post-internalization trafficking. Br J Pharmacol. 2015;172:615-29 pubmed publisher
Erbs E, Faget L, Scherrer G, Matifas A, Filliol D, Vonesch J, et al. A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks. Brain Struct Funct. 2015;220:677-702 pubmed publisher
Pradhan A, Smith M, Zyuzin J, Charles A. δ-Opioid receptor agonists inhibit migraine-related hyperalgesia, aversive state and cortical spreading depression in mice. Br J Pharmacol. 2014;171:2375-84 pubmed publisher
Milan Lobo L, Enquist J, van Rijn R, Whistler J. Anti-analgesic effect of the mu/delta opioid receptor heteromer revealed by ligand-biased antagonism. PLoS ONE. 2013;8:e58362 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Burbassi S, Sengupta R, Meucci O. Alterations of CXCR4 function in ?-opioid receptor-deficient glia. Eur J Neurosci. 2010;32:1278-88 pubmed publisher
Butelman E, Rus S, Prisinzano T, Kreek M. The discriminative effects of the kappa-opioid hallucinogen salvinorin A in nonhuman primates: dissociation from classic hallucinogen effects. Psychopharmacology (Berl). 2010;210:253-62 pubmed publisher
Pacheco D, Klein A, Perez A, Pacheco C, de Francischi J, Reis G, et al. Central antinociception induced by mu-opioid receptor agonist morphine, but not delta- or kappa-, is mediated by cannabinoid CB1 receptor. Br J Pharmacol. 2009;158:225-31 pubmed publisher
Markkanen P, Petäjä Repo U. N-glycan-mediated quality control in the endoplasmic reticulum is required for the expression of correctly folded delta-opioid receptors at the cell surface. J Biol Chem. 2008;283:29086-98 pubmed publisher
da Fonseca Pacheco D, Klein A, de Castro Perez A, da Fonseca Pacheco C, de Francischi J, Duarte I. The mu-opioid receptor agonist morphine, but not agonists at delta- or kappa-opioid receptors, induces peripheral antinociception mediated by cannabinoid receptors. Br J Pharmacol. 2008;154:1143-9 pubmed publisher
Scherrer G, Tryoen Toth P, Filliol D, Matifas A, Laustriat D, Cao Y, et al. Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo. Proc Natl Acad Sci U S A. 2006;103:9691-6 pubmed
Sluka K, Rohlwing J, Bussey R, Eikenberry S, Wilken J. Chronic muscle pain induced by repeated acid Injection is reversed by spinally administered mu- and delta-, but not kappa-, opioid receptor agonists. J Pharmacol Exp Ther. 2002;302:1146-50 pubmed
Gomes I, Jordan B, Gupta A, Trapaidze N, Nagy V, Devi L. Heterodimerization of mu and delta opioid receptors: A role in opiate synergy. J Neurosci. 2000;20:RC110 pubmed
product information
master code :
764
SKU :
0764/10
product name :
SNC 80
unit size :
10 mg (also 50 mg)
description :
Highly selective non-peptide agonist
target :
delta Opioid Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
449.64
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SNC 80 is a highly selective and potent non-peptide -opioid agonist, 2000-fold selective over u -opioid receptors.
top caption :
Highly selective non-peptide agonist
extended description :
Highly selective non-peptide agonist
chemical name text :
(+)-4-[( R)- -((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
formula :
C28H39N3O2
formula text :
C28H39N3O2
cas num :
156727-74-1
USD :
292 USD
product details :
Highly selective non-peptide agonist
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK