product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
TTNPB
catalog :
0761
quantity :
10 mg (also 50 mg)
price :
170 USD
more info or order :
citations: 7
Reference
Cordeiro T, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, et al. Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression. Structure. 2019;: pubmed publisher
Wang B, Fu X, Zhu M, Du M. Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation. J Mol Cell Biol. 2017;9:338-349 pubmed publisher
Chronopoulos A, Robinson B, Sarper M, Cortés E, Auernheimer V, Lachowski D, et al. ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion. Nat Commun. 2016;7:12630 pubmed publisher
Zhang L, Yin J, Yeh H, Ma N, Lee G, Chen X, et al. Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons. Cell Stem Cell. 2015;17:735-47 pubmed publisher
Francipane M, Lagasse E. The lymph node as a new site for kidney organogenesis. Stem Cells Transl Med. 2015;4:295-307 pubmed publisher
Thomas A, Henry J. Retinoic acid regulation by CYP26 in vertebrate lens regeneration. Dev Biol. 2014;386:291-301 pubmed publisher
Tay S, Dickmann L, Dixit V, Isoherranen N. A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation. Mol Pharmacol. 2010;77:218-27 pubmed publisher
product information
brand :
Tocris
master code :
0761
SKU :
0761/10
product name :
TTNPB
description :
Retinoic acid analog; RAR agonist
target :
Retinoic Acid Receptor Agonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
348.48
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Extremely potent analog of retinoic acid, selective for the retinoic acid receptor (RAR) subtype. Enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs).
catalog number base :
761
product keywords :
Retinoic acid analogs agonists RAR Receptors Ro 13-7410 Ro 13-7410 Retinoic Acid Receptors Stem Cell Reprogramming 0761,
extended description :
Retinoic acid analog; RAR agonist
chemical name text :
4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid
formula :
C 24 H 28 O 2
formula text :
C24H28O2
cas num :
71441-28-6
2020 USD :
166
2021 USD :
170 USD
alt names :
Ro 13-7410
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK