product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0761/10
catalog :
0761/10
quantity :
10 mg (also 50 mg)
price :
221 USD
more info or order :
citations: 9
Reference
Cordeiro T, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, et al. Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression. Structure. 2019;: pubmed publisher
Wang B, Fu X, Zhu M, Du M. Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation. J Mol Cell Biol. 2017;9:338-349 pubmed publisher
Chronopoulos A, Robinson B, Sarper M, Cortés E, Auernheimer V, Lachowski D, et al. ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion. Nat Commun. 2016;7:12630 pubmed publisher
Zhang L, Yin J, Yeh H, Ma N, Lee G, Chen X, et al. Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons. Cell Stem Cell. 2015;17:735-47 pubmed publisher
Francipane M, Lagasse E. The lymph node as a new site for kidney organogenesis. Stem Cells Transl Med. 2015;4:295-307 pubmed publisher
Whelan J, Wang L, Chen J, Metts M, Nasser T, McGoldrick L, et al. Retinoids induce integrin-independent lymphocyte adhesion through RAR-α nuclear receptor activity. Biochem Biophys Res Commun. 2014;454:537-42 pubmed publisher
Thomas A, Henry J. Retinoic acid regulation by CYP26 in vertebrate lens regeneration. Dev Biol. 2014;386:291-301 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Tay S, Dickmann L, Dixit V, Isoherranen N. A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation. Mol Pharmacol. 2010;77:218-27 pubmed publisher
product information
master code :
761
SKU :
0761/10
product name :
TTNPB
unit size :
10 mg (also 50 mg)
description :
Retinoic acid analog; RAR agonist
target :
Retinoic Acid Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
348.48
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
TTNPB is an extremely potent analog of retinoic acid, selective for the retinoic acid receptor (RAR) subtype. Enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs).
top caption :
Retinoic acid analog; RAR agonist
extended description :
Retinoic acid analog; RAR agonist
chemical name text :
4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid
formula :
C24H28O2
formula text :
C24H28O2
cas num :
71441-28-6
USD :
221 USD
product details :
Retinoic acid analog; RAR agonist
alt names :
Ro 13-7410
storage :
Desiccate at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK