SM-21 maleate | Tocris Bioscience 0751 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SM-21 maleate

catalog :

0751

quantity :

10 mg (also 50 mg)

price :

159 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Dolma S, Selvadurai H, Lan X, Lee L, Kushida M, Voisin V, et al. Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell. 2016;29:859-873 pubmed publisher
Ishima T, Hashimoto K. Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by ifenprodil: the role of sigma-1 and IP3 receptors. PLoS ONE. 2012;7:e37989 pubmed publisher
Matsumoto R, Pouw B, Mack A, Daniels A, Coop A. Effects of UMB24 and (+/-)-SM 21, putative sigma2-preferring antagonists, on behavioral toxic and stimulant effects of cocaine in mice. Pharmacol Biochem Behav. 2007;86:86-91 pubmed

product information

brand :

Tocris

master code :

0751

SKU :

0751/10

product name :

SM-21 maleate

description :

Presynaptic cholinergic modulator

target :

Acetylcholine Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

453.92

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective 2 antagonist with central effects following systemic administration. Causes increased release of acetylcholine at central muscarinic synapses. Potent analgesic (efficacy comparable to morphine) and nootropic agent.

catalog number base :

751

product keywords :

Selective 2 sigma2 receptors antagonists Presynaptic cholinergic modulators Muscarinic Acetylcholine release Nicotinic nAChR Other Acetylcholine Sigma2 Receptors Non-selective Muscarinics 0751,

extended description :

Presynaptic cholinergic modulator

chemical name text :

( )-Tropanyl 2-(4-chlorophenoxy)butanoate maleate

formula :

C 18 H 24 ClNO 3 .C 4 H 4 O 4

formula text :

C18H24ClNO3.C4H4O4

cas num :

155059-42-0

2020 USD :

154

2021 USD :

159 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage