0751/10 | Tocris Bioscience 0751/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0751/10

catalog :

0751/10

quantity :

10 mg (also 50 mg)

price :

199 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Dolma S, Selvadurai H, Lan X, Lee L, Kushida M, Voisin V, et al. Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell. 2016;29:859-873 pubmed publisher
Ishima T, Hashimoto K. Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by ifenprodil: the role of sigma-1 and IP3 receptors. PLoS ONE. 2012;7:e37989 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Matsumoto R, Pouw B, Mack A, Daniels A, Coop A. Effects of UMB24 and (+/-)-SM 21, putative sigma2-preferring antagonists, on behavioral toxic and stimulant effects of cocaine in mice. Pharmacol Biochem Behav. 2007;86:86-91 pubmed

product information

master code :

751

SKU :

0751/10

product name :

SM-21 maleate

unit size :

10 mg (also 50 mg)

description :

Selective 2 antagonist. Centrally active

target :

Sigma2 Receptor Antagonists

category :

Small Molecules

purity :

99%

observed molecular weight :

453.92

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SM-21 maleate is a potent and selective 2 antagonist with central effects following systemic administration. Causes increased release of acetylcholine at central muscarinic synapses. Potent analgesic (efficacy comparable to morphine) and nootropic agent.

top caption :

Presynaptic cholinergic modulator

extended description :

Selective 2 antagonist. Centrally active

chemical name text :

( )-Tropanyl 2-(4-chlorophenoxy)butanoate maleate

formula :

C18H24ClNO3.C4H4O4

formula text :

C18H24ClNO3.C4H4O4

cas num :

155059-42-0

USD :

199 USD

product details :

Selective 2 antagonist. Centrally active

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage