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company name :
Tocris Bioscience
product type :
chemical
product name :
0728/10
catalog :
0728/10
quantity :
10 mg (also 50 mg)
price :
124 USD
more info or order :
citations: 6
Reference
Du Y, Cramer M, Lee C, Tang J, Muthusamy A, Antonetti D, et al. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB J. 2015;29:2194-204 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Woo R, Li X, Tao Y, Carpenter Hyland E, Huang Y, Weber J, et al. Neuregulin-1 enhances depolarization-induced GABA release. Neuron. 2007;54:599-610 pubmed
Huang Y, Kandel E. 5-Hydroxytryptamine induces a protein kinase A/mitogen-activated protein kinase-mediated and macromolecular synthesis-dependent late phase of long-term potentiation in the amygdala. J Neurosci. 2007;27:3111-9 pubmed
Kato G, Yasaka T, Katafuchi T, Furue H, Mizuno M, Iwamoto Y, et al. Direct GABAergic and glycinergic inhibition of the substantia gelatinosa from the rostral ventromedial medulla revealed by in vivo patch-clamp analysis in rats. J Neurosci. 2006;26:1787-94 pubmed
Xiang Z, Wang L, Kitai S. Modulation of spontaneous firing in rat subthalamic neurons by 5-HT receptor subtypes. J Neurophysiol. 2005;93:1145-57 pubmed
product information
master code :
728
SKU :
0728/10
product name :
RS 23597-190 hydrochloride
unit size :
10 mg (also 50 mg)
description :
5-HT4 antagonist
target :
5-HT4 Receptor Antagonists
category :
Small Molecules
observed molecular weight :
363.28
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
RS 23597-190 hydrochloride is a high affinity, selective competitive antagonist at 5-HT4 receptors.
top caption :
5-HT4 antagonist
extended description :
5-HT4 antagonist
chemical name text :
3-(Piperidin-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride
formula :
C16H23ClN2O3.HCl
formula text :
C16H23ClN2O3.HCl
cas num :
149719-06-2
USD :
124 USD
product details :
5-HT4 antagonist
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK