product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Pyrrolidinedithiocarbamate ammonium
catalog :
0727
quantity :
50 mg
price :
84 USD
more info or order :
citations: 8
Reference
Li X, Chen W, Li P, Wei J, Cheng Y, Liu P, et al. Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression. Theranostics. 2017;7:4671-4688 pubmed publisher
Nadeem A, Ahmad S, Al Harbi N, Fardan A, El Sherbeeny A, Ibrahim K, et al. IL-17A causes depression-like symptoms via NFκB and p38MAPK signaling pathways in mice: Implications for psoriasis associated depression. Cytokine. 2017;97:14-24 pubmed publisher
Ishizuka E, Filgueiras L, Rios F, Serezani C, Jancar S. PAFR activation of NF-?B p65 or p105 precursor dictates pro- and anti-inflammatory responses during TLR activation in murine macrophages. Sci Rep. 2016;6:32092 pubmed publisher
Wang Y, Cai J, Zeng X, Chen Y, Yan W, Ouyang Y, et al. Downregulation of toll-like receptor 4 induces suppressive effects on hepatitis B virus-related hepatocellular carcinoma via ERK1/2 signaling. BMC Cancer. 2015;15:821 pubmed publisher
Lin W, Chen C, Huang Y, Chao L, Chao J, Lin Y, et al. Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis. Sci Rep. 2015;5:12463 pubmed publisher
Clement M, Fornasa G, Guedj K, Ben Mkaddem S, Gaston A, Khallou Laschet J, et al. CD31 is a key coinhibitory receptor in the development of immunogenic dendritic cells. Proc Natl Acad Sci U S A. 2014;111:E1101-10 pubmed publisher
Muxel S, Pires Lapa M, Monteiro A, Cecon E, Tamura E, Floeter Winter L, et al. NF-κB drives the synthesis of melatonin in RAW 264.7 macrophages by inducing the transcription of the arylalkylamine-N-acetyltransferase (AA-NAT) gene. PLoS ONE. 2012;7:e52010 pubmed publisher
Birmingham J, Busik J, Hansen Smith F, Fenton J. Novel mechanism for obesity-induced colon cancer progression. Carcinogenesis. 2009;30:690-7 pubmed publisher
product information
brand :
Tocris
master code :
0727
SKU :
0727/50
product name :
Pyrrolidinedithiocarbamate ammonium
description :
Inhibits NF- B, prevents increase in NOS mRNA
target :
NFkB/IkB Inhibitors
category :
Small Molecules
unit size :
50 mg
observed molecular weight :
164.28
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
This inhibitor of nuclear factor B (NF- B) prevents the increase in NO-synthase mRNA by interleukin-1, without affecting the formation of NO-synthase mRNA produced by cAMP.
catalog number base :
727
product keywords :
inhibitors inhibits NF- B NF-kappaB NF-kB NOS mRNA NF B NFkappaB Nitric Oxide Signaling Signalling I B IkappaB Nuclear Factor Kappa B Transcription Factors PDTC Other Nitric Oxide NF-kB/IkB 0727,
extended description :
Inhibits NF- B, prevents increase in NOS mRNA
formula :
C 5 H 12 N 2 S 2
formula text :
C5H12N2S2
cas num :
5108-96-3
2020 USD :
82
2021 USD :
84 USD
alt names :
PDTC
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK