product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
Retinoic acid
catalog :
0695
quantity :
50 mg
price :
82 USD
more info or order :
citations: 6
Reference
Li X, Tao Y, Bradley R, Du Z, Tao Y, Kong L, et al. Fast Generation of Functional Subtype Astrocytes from Human Pluripotent Stem Cells. Stem Cell Reports. 2018;11:998-1008 pubmed publisher
Bohnenpoll T, Weiss A, Labuhn M, Lüdtke T, Trowe M, Kispert A. Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017;7:14803 pubmed publisher
Jaako K, Waniek A, Parik K, Klimaviciusa L, Aonurm Helm A, Noortoots A, et al. Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro. J Cell Sci. 2016;129:3792-3802 pubmed
Lewis H, Liddle J, Coote J, Atkinson S, Barker M, Bax B, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015;11:189-91 pubmed publisher
Davies W, Tay B, Zheng L, Danks J, Brenner S, Foster R, et al. Evolution and functional characterisation of melanopsins in a deep-sea chimaera (elephant shark, Callorhinchus milii). PLoS ONE. 2012;7:e51276 pubmed publisher
Han A, Heo H, Kwon Y. Berberine promotes axonal regeneration in injured nerves of the peripheral nervous system. J Med Food. 2012;15:413-7 pubmed publisher
product information
brand :
Tocris
master code :
0695
SKU :
0695/50
product name :
Retinoic acid
description :
Endogenous retinoic acid receptor agonist
target :
Retinoic Acid Receptor Agonists
category :
Small Molecules
unit size :
50 mg
purity :
99%
observed molecular weight :
300.44
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Endogenous agonist for retinoic acid receptors (IC50 = 14 nM for RAR , RAR and RAR receptors). Also promotes differentiation of mouse embryonic stem cells (ESCs) into adipocytes, neurons and glia in vitro . Proposed ligand of ROR (Kd = 280 nM). Activates autophagy.
catalog number base :
695
product keywords :
Endogenous retinoic acid receptor agonists modulates PPAR PPARdelta Positive modulators RAR Retinoic Acid Receptors RXR Retinoid X Peroxisome Proliferator-activating PPAR stem cells ATRA all trans retinoic acid trans-retinoic organoids Tretinoin ATRA Retinoic Acid Receptors Retinoid X Receptor Retinoic Acid-related Orphan Receptors ESCs and iPSC Autophagy Organoids 0695,
extended description :
Endogenous retinoic acid receptor agonist
chemical name text :
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
formula :
C 20 H 28 O 2
formula text :
C20H28O2
cas num :
302-79-4
2020 USD :
78
2021 USD :
82 USD
alt names :
Tretinoin, ATRA
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK