product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Dipyridamole
catalog :
0691
quantity :
500 mg
price :
85 USD
more info or order :
citations: 3
Reference
Davidson J, Urban T, Tong S, Twite M, Woodruff A, Wischmeyer P, et al. Alkaline Phosphatase, Soluble Extracellular Adenine Nucleotides, and Adenosine Production after Infant Cardiopulmonary Bypass. PLoS ONE. 2016;11:e0158981 pubmed publisher
Nguyen M, Ross A, Ryals M, Lee S, Venton B. Clearance of rapid adenosine release is regulated by nucleoside transporters and metabolism. Pharmacol Res Perspect. 2015;3:e00189 pubmed publisher
Cunha M, Pazini F, Rosa J, Ramos Hryb A, Oliveira Ã, Kaster M, et al. Creatine, similarly to ketamine, affords antidepressant-like effects in the tail suspension test via adenosine A₁ and A2A receptor activation. Purinergic Signal. 2015;11:215-27 pubmed publisher
product information
brand :
Tocris
master code :
0691
SKU :
0691/500
product name :
Dipyridamole
description :
Adenosine transport inhibitor
target :
Nucleoside Transporter Inhibitors
category :
Small Molecules
unit size :
500 mg
purity :
99%
observed molecular weight :
504.63
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Coronary vasodilator; adenosine transport inhibitor. Phosphodiesterase inhibitor (IC50 values are 0.37, 0.38, 0.45, 0.9 and 4.5 u M for PDE11, 6, 10, 5 and 8 respectively). Inhibits ENT1 and ENT2 (IC50 = 144.8 nM and Ki = 8.18 nM for ENT1).
catalog number base :
691
product keywords :
adenosines transport inhibitors inhibits PDE5 6 10 8 11 ENT1 Uptake Purine Transporters Pyrimidine Equilibrative Nucleoside Monoamine Neurotransmitter Phosphodiesterases vasodilator Nucleoside Transporters Phosphodiesterases 0691,
extended description :
Adenosine transport inhibitor
chemical name text :
2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
formula :
C 24 H 40 N 8 O 4
formula text :
C24H40N8O4
cas num :
58-32-2
2020 USD :
82
2021 USD :
85 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK