product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0691/500
catalog :
0691/500
quantity :
500 mg
price :
108 USD
more info or order :
citations: 5
Reference
Davidson J, Urban T, Tong S, Twite M, Woodruff A, Wischmeyer P, et al. Alkaline Phosphatase, Soluble Extracellular Adenine Nucleotides, and Adenosine Production after Infant Cardiopulmonary Bypass. PLoS ONE. 2016;11:e0158981 pubmed publisher
Nguyen M, Ross A, Ryals M, Lee S, Venton B. Clearance of rapid adenosine release is regulated by nucleoside transporters and metabolism. Pharmacol Res Perspect. 2015;3:e00189 pubmed publisher
Cunha M, Pazini F, Rosa J, Ramos Hryb A, Oliveira Ã, Kaster M, et al. Creatine, similarly to ketamine, affords antidepressant-like effects in the tail suspension test via adenosine A₁ and A2A receptor activation. Purinergic Signal. 2015;11:215-27 pubmed publisher
Mandapathil M, Szczepanski M, Harasymczuk M, Ren J, Cheng D, Jackson E, et al. CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4(+) T effector cells in patients with head and neck squamous cell carcinoma. Oncoimmunology. 2012;1:659-669 pubmed
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
product information
master code :
691
SKU :
0691/500
product name :
Dipyridamole
unit size :
500 mg
description :
Adenosine transport inhibitor
target :
Nucleoside Transporter Inhibitors
category :
Small Molecules
purity :
99%
observed molecular weight :
504.63
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Dipyridamole is a coronary vasodilator; adenosine transport inhibitor. Phosphodiesterase inhibitor (IC50 values are 0.37, 0.38, 0.45, 0.9 and 4.5 u M for PDE11, 6, 10, 5 and 8 respectively). Inhibits ENT1 and ENT2 (IC50 = 144.8 nM and Ki = 8.18 nM for ENT1).
top caption :
Adenosine transport inhibitor
extended description :
Adenosine transport inhibitor
chemical name text :
2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
formula :
C24H40N8O4
formula text :
C24H40N8O4
cas num :
58-32-2
USD :
108 USD
product details :
Adenosine transport inhibitor
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK