0686/100 | Tocris Bioscience 0686/100 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0686/100

catalog :

0686/100

quantity :

100 mg

price :

178 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
de Souza F, Busquet N, Blatner M, Maclean K, Restrepo D. Galantamine improves olfactory learning in the Ts65Dn mouse model of Down syndrome. Sci Rep. 2011;1:137 pubmed publisher

product information

master code :

686

SKU :

0686/100

product name :

Galanthamine hydrobromide

unit size :

100 mg

description :

Cholinesterase inhibitor

target :

Cholinesterase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

368.27

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Prevents -amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. Long-term administration reduces amyloid precursor protein deposition and neurodegeneration in a mouse model of Alzheimer s disease.

top caption :

Cholinesterase inhibitor

extended description :

Cholinesterase inhibitor

chemical name text :

4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide

formula :

C17H21NO3.HBr

formula text :

C17H21NO3.HBr

cas num :

4/4/53

USD :

178 USD

product details :

Cholinesterase inhibitor

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage