product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Diltiazem hydrochloride
catalog :
0685
quantity :
1 g
price :
107 USD
more info or order :
citations: 5
Reference
Begam M, Collier A, Mueller A, Roche R, Galen S, Roche J. Diltiazem improves contractile properties of skeletal muscle in dysferlin-deficient BLAJ mice, but does not reduce contraction-induced muscle damage. Physiol Rep. 2018;6:e13727 pubmed publisher
Hernández Cascales J. Resveratrol enhances the inotropic effect but inhibits the proarrhythmic effect of sympathomimetic agents in rat myocardium. Peerj. 2017;5:e3113 pubmed publisher
Lobeck I, Donnelly B, Dupree P, Mahé M, McNeal M, Mohanty S, et al. Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes. Virology. 2016;499:185-195 pubmed publisher
Cramer S, Popa L, Carter R, Chen G, Ebner T. Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse. J Neurosci. 2015;35:5664-79 pubmed publisher
Fransen P, Van Hove C, Leloup A, Martinet W, De Meyer G, Lemmens K, et al. Dissecting out the complex Ca2+-mediated phenylephrine-induced contractions of mouse aortic segments. PLoS ONE. 2015;10:e0121634 pubmed publisher
product information
brand :
Tocris
master code :
0685
SKU :
0685/1G
product name :
Diltiazem hydrochloride
description :
CaV1.x blocker
target :
Voltage-gated Calcium Channel Blockers
category :
Small Molecules
unit size :
1 g
purity :
99%
observed molecular weight :
450.98
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Antihypertensive and cardioprotective agent; an inhibitor of L-type Ca2+ channels.
catalog number base :
685
product keywords :
Ca2+ channel blockers L-type Calcium CaV Channels voltage-gated voltage-dependent anti-hypertensive cardioprotective Cav1.x Channels 0685, Voltage-gated calcium channel blocker, voltage gated calcium channel, high-voltage activated Ca2+ channel, high voltage gated ca2+ channel
extended description :
CaV1.x blocker
chemical name text :
(2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride
formula :
C 22 H 26 N 2 O 4 S.HCl
formula text :
C22H26N2O4S.HCl
cas num :
33286-22-5
2020 USD :
102
2021 USD :
107 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK