0684/10 | Tocris Bioscience 0684/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0684/10

catalog :

0684/10

quantity :

10 mg

price :

394 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Noviello C, Gharpure A, Mukhtasimova N, Cabuco R, Baxter L, Borek D, et al. Structure and gating mechanism of the α7 nicotinic acetylcholine receptor. Cell. 2021;184:2121-2134.e13 pubmed publisher
Wu M, Liu C, Joiner W. Structural Analysis and Deletion Mutagenesis Define Regions of QUIVER/SLEEPLESS that Are Responsible for Interactions with Shaker-Type Potassium Channels and Nicotinic Acetylcholine Receptors. PLoS ONE. 2016;11:e0148215 pubmed publisher
Sexton T, Golczak M, Palczewski K, Van Gelder R. Melanopsin is highly resistant to light and chemical bleaching in vivo. J Biol Chem. 2012;287:20888-97 pubmed publisher
Williams D, Brain K, Cunnane T. The effect of epibatidine on spontaneous and evoked neurotransmitter release in the mouse and guinea pig isolated vas deferens. Br J Pharmacol. 2007;150:906-12 pubmed
Beckel J, Kanai A, Lee S, de Groat W, Birder L. Expression of functional nicotinic acetylcholine receptors in rat urinary bladder epithelial cells. Am J Physiol Renal Physiol. 2006;290:F103-10 pubmed

product information

master code :

684

SKU :

0684/10

product name :

(+/-)-Epibatidine

unit size :

10 mg

description :

High affinity nAChR agonist

target :

Additional Nicotinic Receptor Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

208.69

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

( )-Epibatidine is a high affinity nicotinic agonist (Ki values are 0.02 and 233 nM for 4 2 and 7 nicotinic receptors respectively). Analgesic.

top caption :

High affinity nAChR agonist

extended description :

High affinity nAChR agonist

chemical name text :

( )-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane

formula :

C11H13ClN2

formula text :

C11H13ClN2

cas num :

148152-66-3

USD :

394 USD

product details :

High affinity nAChR agonist

storage :

Desiccate at +4░C

more info or order :

Tocris Bioscience product webpage