2-Phenylmelatonin | Tocris Bioscience 0680 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

2-Phenylmelatonin

catalog :

0680

quantity :

10 mg (also 50 mg)

price :

145 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Akoume M, Elbakry M, Veillette M, Franco A, Nada D, Labelle H, et al. A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep. 2019;9:10074 pubmed publisher
Stauch B, Johansson L, McCorvy J, Patel N, Han G, Huang X, et al. Structural basis of ligand recognition at the human MT1 melatonin receptor. Nature. 2019;569:284-288 pubmed publisher
Johansson L, Stauch B, McCorvy J, Han G, Patel N, Huang X, et al. XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity. Nature. 2019;569:289-292 pubmed publisher

product information

brand :

Tocris

master code :

0680

SKU :

0680/10

product name :

2-Phenylmelatonin

description :

Potent melatonin agonist

target :

Melatonin (MT) Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

308.38

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Highly potent melatonin agonist; displays higher affinity and greater potency than melatonin itself. The EC50 values for G protein activation in MT1 and MT2-transfected cells are 65 and 58 pM respectively.

catalog number base :

680

product keywords :

Potent melatonin agonists MT Receptors Melatonin (MT) Receptors 0680,

extended description :

Potent melatonin agonist

chemical name text :

N-[2-(5-Methoxy-2-phenylindol-3-yl)ethyl]acetamide

formula :

C 19 H 20 N 2 O 2

formula text :

C19H20N2O2

cas num :

151889-03-1

2020 USD :

145

2021 USD :

145 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage