product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0680/10
catalog :
0680/10
quantity :
10 mg (also 50 mg)
price :
182 USD
more info or order :
citations: 4
Reference
Akoume M, Elbakry M, Veillette M, Franco A, Nada D, Labelle H, et al. A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep. 2019;9:10074 pubmed publisher
Stauch B, Johansson L, McCorvy J, Patel N, Han G, Huang X, et al. Structural basis of ligand recognition at the human MT1 melatonin receptor. Nature. 2019;569:284-288 pubmed publisher
Johansson L, Stauch B, McCorvy J, Han G, Patel N, Huang X, et al. XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity. Nature. 2019;569:289-292 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
product information
master code :
680
SKU :
0680/10
product name :
2-Phenylmelatonin
unit size :
10 mg (also 50 mg)
description :
Potent melatonin agonist
target :
Melatonin (MT) Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
308.38
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
2-Phenylmelatonin is a highly potent melatonin agonist; displays higher affinity and greater potency than melatonin itself. The EC50 values for G protein activation in MT1 and MT2-transfected cells are 65 and 58 pM respectively.
top caption :
Potent melatonin agonist
extended description :
Potent melatonin agonist
chemical name text :
N-[2-(5-Methoxy-2-phenylindol-3-yl)ethyl]acetamide
formula :
C19H20N2O2
formula text :
C19H20N2O2
cas num :
151889-03-1
USD :
182 USD
product details :
Potent melatonin agonist
storage :
Store at +4░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK