product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
AH 6809
catalog :
0671
quantity :
10 mg (also 50 mg)
price :
189 USD
more info or order :
citations: 6
Reference
Liu B, Tai Y, Caceres A, Achanta S, Balakrishna S, Shao X, et al. Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice. PLoS ONE. 2016;11:e0165200 pubmed publisher
Jansen S, Holman R, Hedemann I, Frankes E, Elzinga C, Timens W, et al. Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization. J Cell Mol Med. 2015;19:210-26 pubmed publisher
Passafaro D, Sterin Borda L, Reina S, Borda E. Cholinergic Autoantibodies from Primary Sjögren's Syndrome Inhibit Mucin Production via Phospholipase C and Cyclooxygenase-2 In the Rat Submandibular Gland. Dent Res J (Isfahan). 2011;8:138-45 pubmed
Chia E, Kagota S, Wijekoon E, McGuire J. Protection of protease-activated receptor 2 mediated vasodilatation against angiotensin II-induced vascular dysfunction in mice. BMC Pharmacol. 2011;11:10 pubmed publisher
Schaafsma D, Gosens R, Ris J, Zaagsma J, Meurs H, Nelemans S. Insulin induces airway smooth muscle contraction. Br J Pharmacol. 2007;150:136-42 pubmed
Walsh M, Kinsella B. Regulation of the human prostanoid TPalpha and TPbeta receptor isoforms mediated through activation of the EP(1) and IP receptors. Br J Pharmacol. 2000;131:601-9 pubmed
product information
brand :
Tocris
master code :
0671
SKU :
0671/10
product name :
AH 6809
description :
EP1 and EP2 receptor antagonist
target :
Prostanoid Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
298.3
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Antagonist at prostaglandin EP1 (pA2 = 6.8) and EP2 (Ki = 350 nM) receptors. Also weakly inhibits DP receptors (pA2 = 4.45).
catalog number base :
671
product keywords :
EP1 EP2 receptor antagonists DP Receptors prostanoid receptors prostaglandins prostacyclins eicosanoids AH6809 Prostanoid Receptors 0671,
extended description :
EP1 and EP2 receptor antagonist
chemical name text :
6-Isopropoxy-9-xanthone-2-carboxylic acid
formula :
C 17 H 14 O 5
formula text :
C17H14O5
cas num :
33458-93-4
2020 USD :
185
2021 USD :
189 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK