PK 11195 | Tocris Bioscience 0670 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PK 11195

catalog :

0670

quantity :

10 mg (also 50 mg)

price :

86 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Gut P, Baeza Raja B, Andersson O, Hasenkamp L, Hsiao J, Hesselson D, et al. Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism. Nat Chem Biol. 2013;9:97-104 pubmed publisher
Anderson L, Dring A, Hamel L, Stoner M. Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR). Toxicol Lett. 2011;202:148-54 pubmed publisher
Sutter A, Maaser K, Barthel B, Scherubl H. Ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in oesophageal cancer cells: involvement of the p38MAPK signalling pathway. Br J Cancer. 2003;89:564-72 pubmed

product information

brand :

Tocris

master code :

0670

SKU :

0670/10

product name :

PK 11195

description :

Antagonist at peripheral benzodiazepine receptors

target :

Translocator Protein Ligands

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

352.86

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Possesses high affinity for the peripheral benzodiazepine receptor (PBR, TSPO) without binding to other known neurotransmitter receptors. Also inhibits the human constitutive androstane receptor (hCAR).

catalog number base :

670

product keywords :

antagonists peripheral benzodiazepine receptors GABAA Receptors PK11195 PBR TSPO Constitutive Androstane Receptor Translocator Protein 0670,

extended description :

Antagonist at peripheral benzodiazepine receptors

chemical name text :

1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide

formula :

C 21 H 21 ClN 2 O

formula text :

C21H21ClN2O

cas num :

85532-75-8

2020 USD :

2021 USD :

86 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage