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company name :
Tocris Bioscience
product type :
chemical
product name :
0665/100
catalog :
0665/100
quantity :
100 mg
price :
106 USD
more info or order :
citations: 23
Reference
Cameron R, Peterson Y, Beeson C, Schnellmann R. Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol. Sci Rep. 2017;7:10578 pubmed publisher
Shen X, Burguillos M, Osman A, Frijhoff J, Carrillo Jimenez A, Kanatani S, et al. Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype. Nat Immunol. 2016;17:1282-1290 pubmed publisher
Cramer S, Popa L, Carter R, Chen G, Ebner T. Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse. J Neurosci. 2015;35:5664-79 pubmed publisher
Haam J, Halmos K, Di S, Tasker J. Nutritional state-dependent ghrelin activation of vasopressin neurons via retrograde trans-neuronal-glial stimulation of excitatory GABA circuits. J Neurosci. 2014;34:6201-13 pubmed publisher
Bucher E, Fox M, Kim L, Kirkpatrick D, Rodeberg N, Belle A, et al. Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis. J Cereb Blood Flow Metab. 2014;34:1128-37 pubmed publisher
Elks P, Brizee S, van der Vaart M, Walmsley S, van Eeden F, Renshaw S, et al. Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism. PLoS Pathog. 2013;9:e1003789 pubmed publisher
Bice J, Keim Y, Stasch J, Baxter G. NO-independent stimulation or activation of soluble guanylyl cyclase during early reperfusion limits infarct size. Cardiovasc Res. 2014;101:220-8 pubmed publisher
Townsend E, Emala C. Quercetin acutely relaxes airway smooth muscle and potentiates ?-agonist-induced relaxation via dual phosphodiesterase inhibition of PLC? and PDE4. Am J Physiol Lung Cell Mol Physiol. 2013;305:L396-403 pubmed publisher
Vaish M, Singh V. Antioxidant Functions of Nitric Oxide Synthase in a Methicillin Sensitive Staphylococcus aureus. Int J Microbiol. 2013;2013:312146 pubmed publisher
Gross G, Hsu A, Pfeiffer A, Nithipatikom K. Roles of endothelial nitric oxide synthase (eNOS) and mitochondrial permeability transition pore (MPTP) in epoxyeicosatrienoic acid (EET)-induced cardioprotection against infarction in intact rat hearts. J Mol Cell Cardiol. 2013;59:20-9 pubmed publisher
Orru M, Guitart X, Karcz Kubicha M, Solinas M, Justinova Z, Barodia S, et al. Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humans. Neuropharmacology. 2013;67:476-84 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Dai M, Yang Y, Shi X. Lactate dilates cochlear capillaries via type V fibrocyte-vessel coupling signaled by nNOS. Am J Physiol Heart Circ Physiol. 2011;301:H1248-54 pubmed publisher
Gallo E, Iadecola C. Neuronal nitric oxide contributes to neuroplasticity-associated protein expression through cGMP, protein kinase G, and extracellular signal-regulated kinase. J Neurosci. 2011;31:6947-55 pubmed publisher
Sunters A, Armstrong V, Zaman G, Kypta R, Kawano Y, Lanyon L, et al. Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 r. J Biol Chem. 2010;285:8743-58 pubmed publisher
Huang C, Hsu K. Activation of muscarinic acetylcholine receptors induces a nitric oxide-dependent long-term depression in rat medial prefrontal cortex. Cereb Cortex. 2010;20:982-96 pubmed publisher
Lou T, Singh M, Mackie A, Li W, Pace B. Hydroxyurea generates nitric oxide in human erythroid cells: mechanisms for gamma-globin gene activation. Exp Biol Med (Maywood). 2009;234:1374-82 pubmed publisher
Pearson T, Warren A, Barrett D, Khan R. Detection of EETs and HETE-generating cytochrome P-450 enzymes and the effects of their metabolites on myometrial and vascular function. Am J Physiol Endocrinol Metab. 2009;297:E647-56 pubmed publisher
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Chen W, Sulcove J, Frank I, Jaffer S, Ozdener H, Kolson D. Development of a human neuronal cell model for human immunodeficiency virus (HIV)-infected macrophage-induced neurotoxicity: apoptosis induced by HIV type 1 primary isolates and evidence for involvement of the Bcl-2/Bcl-xL-sensitive intrinsic apoptos. J Virol. 2002;76:9407-19 pubmed
Casado M, Dieudonne S, Ascher P. Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse. Proc Natl Acad Sci U S A. 2000;97:11593-7 pubmed
product information
master code :
665
SKU :
0665/100
product name :
L-NAME hydrochloride
unit size :
100 mg
description :
Non-selective NOS inhibitor
target :
Additional NOS Inhibitors
category :
Small Molecules
observed molecular weight :
269.69
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
L-NAME hydrochloride is a NO synthase inhibitor.
top caption :
Non-selective NOS inhibitor
extended description :
Non-selective NOS inhibitor
chemical name text :
NG-Nitro-L-arginine methyl ester hydrochloride
formula :
C7H15N5O4.HCl
formula text :
C7H15N5O4.HCl
cas num :
51298-62-5
USD :
106 USD
product details :
Non-selective NOS inhibitor
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK