FGIN-1-27 | Tocris Bioscience 0658 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FGIN-1-27

catalog :

0658

quantity :

10 mg (also 50 mg)

price :

129 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Sutter A, Maaser K, Barthel B, Scherubl H. Ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in oesophageal cancer cells: involvement of the p38MAPK signalling pathway. Br J Cancer. 2003;89:564-72 pubmed

product information

brand :

Tocris

master code :

0658

SKU :

0658/10

product name :

FGIN-1-27

description :

Potent, specific ligand for mitochondrial DBI receptor

target :

Other Translocator Protein Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

436.61

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.

catalog number base :

658

product keywords :

Potent specific ligand mitochondrial DBI receptor GABAA Receptors FGIN127 GABAA Receptors Translocator Protein 0658,

extended description :

Potent, specific ligand for mitochondrial DBI receptor

chemical name text :

N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide

formula :

C 28 H 37 FN 2 O

formula text :

C28H37FN2O

cas num :

142720-24-9

2020 USD :

126

2021 USD :

129 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage